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Molecular basis of metal ions – amyloids interaction


Principal investigator: C. Hureau

We study the coordination of Cu(I/II) and Zn(II) with the amyloid-β peptide involved in Alzheimer’s disease and how it could impact the two deleterious processes at the origin of the pathology, i.e. oxidative stress and peptide assembly. A possible synergetic link between the two processes is also under investigation.


Laboratoire de chimie de coordination du CNRS

205 route de Narbonne, BP 44099
31077 Toulouse cedex 4