Mechanisms of Plasmodium resistance and therapeutic targets
Malaria is a major public health problem worldwide, with almost 600,000 deaths per year, most of them children under the age of 5. The treatment of this disease…
Chemical synthesis of compounds for therapeutic use
In this context, we have designed and synthesised several families of molecules with good antimalarial activity. These molecules are often composed of several ‘fragments’…
Markers of resistance selection
The acquisition of drug resistance capacity by malaria parasites is a process that depends on many factors, both exogenous, such as drug quality…
Alzheimer’s disease and Wilson’s disease
There is currently no effective medication for Alzheimer’s disease. This neurodegenerative disease is characterised by a loss of endogenous copper regulation…