Dendrimers and Heterochemistry (Team M)

LCC

Overview

The “Dendrimers and Heterochemistry” team is interested in the synthesis and original properties of phosphorus-containing dendritic macromolecular architectures, such as dendrimers, dendrons, branched polymers, etc.

These macromolecular objects are the subject of various characterizations, and their properties in the fields of catalysis, materials and biology are of particular attention.

Members of the team

All
Senior researcher, Deputy Director of the LCC

CAMINADE Anne-Marie

Fixed-term contract

AMRI Saber

PhD student

APARICI Charlotte

University professor

BERNARDES-GENISSON Vania

Masters Degree student

BETTIOUI Assia

PhD student

BOUVET Jon

PhD student

BOUVIER Corentin

PhD student

CHEN Dan

Senior Researcher DR2 CNRS

DELAVAUX-NICOT Beatrice

DURRIEU Mathilde
Student

DURRIEU Mathilde

Masters Degree student

FUENTES Chloe

Assistant Professor

HAMEAU Aurelien

Student

HICHAME Zahira

Guest

KOUR Jaspreet

Researcher

LAURENT Regis

Student

LAVERDURE Marie

Senior researcher emeritus

MAJORAL Jean-Pierre

Research engineer

MARAVAL Valérie

Assistant engineer

MARTIN-MOTHES Emmanuelle

Assistant engineer

MENENDEZ Christophe

MICHAUT Juliette
Student

MICHAUT Juliette

PhD student

MILEWSKI Max

Masters Degree student

MILOT Baptiste

Senior Researcher DR2 CNRS

MOINEAU-CHANE CHING Kathleen

Research engineer

OUKHRIB Abdelouahd

PhD student

PETRICCONE Massimo

Student

RICHAGNEUX Camille

Senior Researcher DR2 CNRS

RODRIGUEZ Manuel

SHULHA Yaroslav
Student

SHULHA Yaroslav

SUROV Dmytro
PhD student

SUROV Dmytro

Student

TOUNSI Imène

Senior Researcher

TURRIN Cédric-Olivier

Visiting professor

VOITENKO Zoia

PhD student

YAO Zhenyu

Doctorant

ZOU Yu

No Results Found

Senior researcher, Deputy Director of the LCC

CAMINADE Anne-Marie

ORCID number : 0000-0001-8487-3578

Comprehensive CV

Anne-Marie Caminade is Director of Research Exceptional Class at the CNRS (DRCE since 2014), Deputy Director of the LCC (DUA since 2021), and Head of the “Dendrimers and Heterochemistry” team (since 2006). She was recently named Chevalier de la Légion d’Honneur and received the Grand Prix Le Bel de la SCF (2021). Her main research theme concerns phosphorus macromolecules, in particular dendrimers, and their applications for catalysis, materials, and nanomedicine.

Email:anne-marie.caminade(at)lcc-toulouse.fr

Phone:05.61.33.31.25

Office:G070

Team:M

Fixed-term contract

AMRI Saber

Email:saber.amri(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

PhD student

APARICI Charlotte

Email:charlotte.aparici(at)lcc-toulouse.fr

Phone:05.61.33.31.50

Office:G175

Team:M

University professor

BERNARDES-GENISSON Vania

View detailed profile

ORCID number: 0000-0002-2937-6787

Email:vania.bernardes-genisson(at)lcc-toulouse.fr

Phone:05.61.33.31.33

Office:G072

Team:M

Masters Degree student

BETTIOUI Assia

Email:assia.bettioui(at)lcc-toulouse.fr

Phone:05.61.33.31.33

Office:G169

Team:M

PhD student

BOUVET Jon

Email:jon.bouvet(at)lcc-toulouse.fr

Phone:05.61.33.31.33

Office:G169

Team:M

PhD student

BOUVIER Corentin

ORCID number: 0000-0002-3344-6856

Corentin holds a Master degree in Molecular Chemistry from the University of Rennes, and a Master degree in Chemistry and Living Technologies from the Ecole Nationale Supérieure de Chimie de Rennes. His previous experience in medicinal chemistry led him to work with Sanofi and Yale University. His PhD project aims at developing new therapeutic approaches of Mantle Cell Lymphoma relying on multivalent molecular platforms that target proteaphagy.

Email:corentin.bouvier(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

PhD student

CHEN Dan

Email:dan.chen(at)lcc-toulouse.fr

Phone:05.61.33.31.50

Office:G175

Team:M

Senior Researcher DR2 CNRS

DELAVAUX-NICOT Beatrice

ORCID number : 0000-0001-9728-8626

Béatrice Delavaux-Nicot is currently a Research Director at CNRS.

She earned her PhD from Paul Sabatier University in Toulouse in 1986 and obtained her Habilitation to Supervise Research from UPS in 1997. Having worked in seven different research groups at the French Institute of Petroleum (Rueil Malmaison), the Atomic Energy Commission (Saclay), and the LCC (Toulouse), she has contributed to the development of various themes in coordination chemistry.

Her molecular focus ranges from simple complexes to organized supramolecular systems, including nanomolecules like dendrimers. Synthesis, characterization, reactivity, physicochemical properties, and structure-property correlations are at the core of her studies. Electrochemistry and luminescence, along with their potential applications in solution or solid state, are areas of particular interest.

Most molecular systems involve energy or electron transfers, designed for producing original ion detectors in solutions, “greener” OLEDs, or original and high-performing luminescent molecular materials.

Collaboration with different teams is an essential contribution to her activity.

Email:beatrice.delavaux-nicot(at)lcc-toulouse.fr

Phone:05.61.33.31.33

Office:G072

Team:M

Student

DURRIEU Mathilde

Email:mathilde.durrieu(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

Masters Degree student

FUENTES Chloe

Email:chloe.fuentes(at)lcc-toulouse.fr

Phone:05.61.33.32.33

Office:G079

Team:M

Assistant Professor

HAMEAU Aurelien

Email:aurelien.hameau(at)lcc-toulouse.fr

Phone:05.61.33.32.33

Office:G079

Team:M

Student

HICHAME Zahira

Email:zahira.hichame(at)lcc-toulouse.fr

Phone:05.61.33.32.33

Office:G079

Team:M

Guest

KOUR Jaspreet

Email:jaspreet.kour(at)lcc-toulouse.fr

Phone:05.61.33.31.33

Office:G072

Team:M

Researcher

LAURENT Regis

ORCID number: 0000-0001-6742-1000

Régis Laurent was born in Porvoo (Finland) and studied chemistry at the Univ. of Toulouse where he received his PhD in 1994 (microwave activation in chemistry). After post-doctoral studies at the Univ. of Saarbrücken, and at the Univ. of Toulouse, he got in 1996 a position at the CNRS in the team Dendrimers and Heterochemistry. He is involved since 2010 in Technopolym (service for polymer characterization) and is since 2021 deputy director of the Institut de Chimie de Toulouse, UAR 2599.

Email:regis.laurent(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

Student

LAVERDURE Marie

Email:marie.laverdure(at)lcc-toulouse.fr

Phone:05.61.33.31.25

Office:G070

Team:M

Senior researcher emeritus

MAJORAL Jean-Pierre

ORCID number: 0000-0002-0971-817X

Comprehensive CV

Email:jean-pierre.majoral(at)lcc-toulouse.fr

Phone:05.61.33.31.23

Office:G078

Team:M

Research engineer

MARAVAL Valérie

ORCID number: 0000-0003-0900-7332

Email:valerie.maraval(at)lcc-toulouse.fr

Phone:05.61.33.31.36

Office:G177

Team:M

Assistant engineer

MARTIN-MOTHES Emmanuelle

Assistant engineer at LCC, my main mission is the synthesis of new molecules.

I have two specialties:

  • Organic syntheses (dendrimers, porphyrins, therapeutic molecules)
  • Organometallic chemistry, with the design of organophosphate and organobor ligands, metallic precursors and catalysis

I intervene in the teams «Activation of Small Molecules» (team N) and «Dendrimere and Heterochemistry» (team M).

Also, I manage the LCC chemolibrary.

Email:emmanuelle.mothes(at)lcc-toulouse.fr

Phone:05.61.33.32.33. et 05.61.33.31.89.

Office:G081/G275

Team:M/N

Assistant engineer

MENENDEZ Christophe

Email:christophe.menendez(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

Student

MICHAUT Juliette

Email:juliette.michaut(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

PhD student

MILEWSKI Max

Email:max.milewski(at)lcc-toulouse.fr

Phone:05.61.33.31.33

Office:G175

Team:M

Masters Degree student

MILOT Baptiste

Email:baptiste.milot(at)lcc-toulouse.fr

Phone:05.61.33.31.36

Office:G173

Team:M

Senior Researcher DR2 CNRS

MOINEAU-CHANE CHING Kathleen

Numéro ORCID : 0000-0001-9478-347X

Comprehensive CV

01/1995: Thesis, Univ. Paris VI _ Design, synthesis and study of phosphorus derivatives for NLO.

1995-1996: post-doc., ITODYS, Univ. Paris7 _ synthesis and electropolymerization of pyrrole derivatives.

1996-2006: ITODYS, Univ. Paris7 _ CNRS researcher (CR); study of electronic interactions in organic pi-conjugated systems.

2006 => LCC, Toulouse _ 2009: Senior Researcher (DR2); organic electronics, organic photovoltaics, grafting of pi-conjugated organic chromophores onto dendrimers.

Email:kathleen.chane(at)lcc-toulouse.fr

Phone:05.61.33.31.36

Office:G177

Team:M

Research engineer

OUKHRIB Abdelouahd

ORCID number: 0000-0001-9962-7927

Abdelouahd OUKHRIB, Ph.D: In 2015, I received my Ph.D in organic chemistry, catalysis and organometallic from Paul Sabatier University of Toulouse-France. My research combines design and development of new macromolecules of interest for the pharmaceutical industry, development of innovative and stimulable biomaterials (vesicles, gels) and development of pharmaceutical formulations for topical use.

Email:abdelouahd.oukhrib(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

PhD student

PETRICCONE Massimo

My name is Massimo Petriccone I’m from Italy and I’m a Ph.D. candidate in joint supervision between the Autonomous University of Barcelona (UAB) and the LCC, within the framework of the CCIMC project funded by the Marie Skłodowska-Curie Actions – European Commission.

Email:massimo.petriccone(at)lcc-toulouse.fr

Phone:05.61.33.31.50

Office:G175

Team:M

Student

RICHAGNEUX Camille

Email:camille.richagneux(at)lcc-toulouse.fr

Phone:05.61.33.31.34

Office:G064

Team:M

Senior Researcher DR2 CNRS

RODRIGUEZ Manuel

ORCID number : 0000-0001-5445-4495

View detailed profile

Manuel S. Rodriguez holds a Ph.D. in Microbiology from Paris 7 University-Pasteur Institute. He continued his career at the Centre for Biomolecular Sciences of the University of St Andrews (UK), Jacques Monod Institute (France), CIC bioGUNE and Inbiomed centers (Spain). His team focuses on the study of the ubiquitin-proteasome system. Manuel is co-coordinator of the European training networks UPStream and UbiCODE, and currently works in collaboration with the Pharmadev laboratory (IRD).

Email:manuel.rodriguez(at)lcc-toulouse.fr

Phone:05.61.33.31.25

Office:G070

Team:M

Student

SHULHA Yaroslav

Email:yaroslav.shulha(at)lcc-toulouse.fr

Phone:05.61.33.31.50

Office:G175

Team:M

PhD student

SUROV Dmytro

Email:dmytro.surov(at)lcc-toulouse.fr

Phone:05.61.33.31.35

Office:B109

Team:M

Student

TOUNSI Imène

Email:imene.tounsi(at)lcc-toulouse.fr

Phone:05.61.33.32.36

Office:G173

Team:M/R

Senior Researcher

TURRIN Cédric-Olivier

ORCID number: 0000-0001-7187-8070

DR2, seconded from the CNRS on a part-time basis, co-founder and President of IMD-Pharma

Email:cedric-olivier.turrin(at)lcc-toulouse.fr

Phone:05.61.33.31.13

Office:B105

Team:M

Visiting professor

VOITENKO Zoia

ORCID number: 0000-0002-2408-6991

Comprehensive CV

Email:voitenko(at)lcc -toulouse.fr

Phone:05.61.33.32.36

Office:G173

Team:M

PhD student

YAO Zhenyu

Email:zhenyu.yao(at)lcc-toulouse.fr

Phone:05.61.33.31.50

Office:G175

Team:M

Doctorant

ZOU Yu

ORCID number: 0000-0002-9703-7461

Email:yu.zou(at)lcc-toulouse.fr

Phone:05.61.33.31.23

Office:G078

Team:M

Research topics

Team news

Publications

2024

The effects of alkyl substitution on the aggregation of π conjugated dyes: spectroscopic study and modelling
Bardi B., Saquet A., Moreau A., Moineau-Chane Ching K., Terenziani F.
Physical Chemistry Chemical Physics 2024,
http://dx.doi.org/10.1039/D4CP01579G
https://hal.science/hal-04606301

A water-soluble polyphosphorhydrazone Janus dendrimer built by “click” chemistry as support for Ru-complexes in catalysis
Cejas-Sánchez J., Caminade A.-M., Kajetanowicz A., Grela K., Sebastián R. M.
Dalton Transactions 2024, 53(21), 9120-9129.
http://dx.doi.org/10.1039/D3DT04376B
https://hal.science/hal-04597712

1,2,3-Triazol-5-ylidene- vs. 1,2,3-triazole-based tricarbonylrhenium(i) complexes: influence of a mesoionic carbene ligand on the electronic and biological properties
Vanucci-Bacqué C., Wolff M., Delavaux-Nicot B., Abdallah A. M., Mallet-Ladeira S., Serpentini C.-L., Bedos-Belval F., Fong K. W., Ng X. Y., Low M. L., Benoist E., Fery-Forgues S.
Dalton Transactions 2024,
http://dx.doi.org/10.1039/D4DT00922C
https://hal.science/hal-04586541

Coordination Chemistry Inspires Molecular Catalysis
Poli R., Caminade A.-M. (Eds).
Zenodo, 2024.
https://doi.org/10.5281/zenodo.10966127
https://hal.science/hal-04548441

Dendritic pyridine–imine copper complexes as metallo-drugs
Laurent R., Maraval V., Bernardes-Génisson V., Caminade A.-M.
Molecules 2024, 29 (8), 1800/1-18.
https://doi.org/10.3390/molecules29081800
https://hal.science/hal-04548084

Multivalent pyrrolidines acting as pharmacological chaperones against Gaucher disease
Borie-Guichot M., Lan Tran M., Garcia V., Oukhrib A., Rodriguez F., Turrin C.-O., Levade T., Génisson Y., Ballereau S., Dehoux C.
Bioorganic Chemistry 2024, 146, 107295/1-9.
https://doi.org/10.1016/j.bioorg.2024.107295
https://hal.science/hal-04536441

Two-photon absorbing dendrimers and their properties—An overview
Maraval V., Caminade A.-M.
International Journal of Molecular Sciences 2024, 25 (6), 3132/1-26.
https://doi.org/10.3390/ijms25063132
https://hal.science/hal-04532522

Two-photon absorbing dendrimers
Maraval V., Caminade A.-M.
Encyclopedia Platform. Bâle (Switzerland), 2024, Entry 56221.
https://encyclopedia.pub/entry/56221
https://hal.science/hal-04532562

From stilbenes to carbo-stilbenes: An encouraging prospect
Zhu C., Saquet A., Maraval V., Bijani C., Cui X., Poater A., Chauvin R.
Chemistry – A European Journal 2024, 30(26), e202400451/1-7.
https://doi.org/10.1002/chem.202400451
https://hal.science/hal-04532883

Selected properties of phosphorus dendrimers: green approaches to catalysis
Caminade A.-M., Maraval V.
Comptes Rendus Chimie 2024, 27 (S2), 1-17.
https://doi.org/10.5802/crchim.277
https://hal.science/hal-04528990

Polycationic phosphorous dendrimer potentiates multiple antibiotics against drug-resistant mycobacterial pathogens
Imran M., Singh S., Ahmad M. N., Malik P., Mukhopadhyay A., Yadav K. S., Gupta U. D., Mugale M. N., Mitra K., Srivastava K. K., Chopra S., Mignani S., Apartsin E., Majoral J.-P., Dasgupta A.
Biomedicine & Pharmacotherapy 2024, 173, 116289/1-12.
https://doi.org/10.1016/j.biopha.2024.116289
https://hal.science/hal-04528925

Breaking bad proteins—discovery approaches and the road to clinic for degraders
Bouvier C., Lawrence R., Cavallo F., Xolalpa W., Jordan A., Hjerpe R., Rodriguez M. S.
Cells 2024, 13 (7), 578/1-37.
https://doi.org/10.3390/cells13070578
https://hal.science/hal-04522952

SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Lachiondo-Ortega S., Rejano-Gordillo C. M., Simon J., Lopitz-Otsoa F., C. Delgado T., Mazan-Mamczarz K., Goikoetxea-Usandizaga N., Zapata-Pavas L. E., García-del Río A., Guerra P., Peña-Sanfélix P., Hermán-Sánchez N., Al-Abdulla R., Fernandez-Rodríguez C., Azkargorta M., Velázquez-Cruz A., Guyon J., Martín C., Zalamea J. D., Egia-Mendikute L., Sanz-Parra A., Serrano-Maciá M., González-Recio I., Gonzalez-Lopez M., Martínez-Cruz L. A., Pontisso P., Aransay A. M., Barrio R., Sutherland J. D., Abrescia N. G. A., Elortza F., Lujambio A., Banales J. M., Luque R. M., Gahete M. D., Palazón A., Avila M. A., G. Marin J. J., De S., Daubon T., Díaz-Quintana A., Díaz-Moreno I., Gorospe M., Rodríguez M. S., Martínez-Chantar M. L.
Cell Reports 2024, 43 (3), 113924/1-20.
https://doi.org/10.1016/j.celrep.2024.113924
https://hal.science/hal-04522023

Stabilization of luminescent mononuclear three-coordinate cui complexes by two distinct cavity-shaped diphosphanes obtained from a single α-cyclodextrin precursor
Phan T.-A., Jouffroy M., Matt D., Armaroli N., Saavedra Moncada A., Bandini E., Delavaux-Nicot B., Nierengarten J.-F., Armspach D.
Chemistry – A European Journal 2023, 30 (7), e202302750/1-9.
https://doi.org/10.1002/chem.202302750
https://hal.science/hal-04322174

Unsymmetrical low-generation cationic phosphorus dendrimers as a nonviral vector to deliver microRNA for breast cancer therapy
Zou Y., Shen S., Karpus A., Sun H., Laurent R., Caminade A.-M., Shen M., Mignani S., Shi X., Majoral J.-P.
Biomacromolecules 2024, 25 (2), 1171-1179.
https://doi.org/10.1021/acs.biomac.3c01169
https://hal.science/hal-04502427

Carboranylphosphines: B9-substituted derivatives with enhanced reactivity for the anchoring to dendrimers
Milewski M., Caminade A.-M., Mallet-Ladeira S., Lledós A., Lönnecke P., Hey-Hawkins E.
Chemistry – A European Journal 2024, 30(13), e202303867/1-8.
https://doi.org/10.1002/chem.202303867
https://hal.science/hal-04428400

SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells
Seoane R., Lama-Díaz T., Romero A. M., El Motiam A., Martínez-Férriz A., Vidal S., Bouzaher Y. H., Blanquer M., Tolosa R. M., Castillo Mewa J., Rodríguez M. S., García-Sastre A., Xirodimas D., Sutherland J. D., Barrio R., Alepuz P., Blanco M. G., Farràs R., Rivas C.
Cellular & Molecular Biology Letters 2024, 29 (1), 15/1-29.
https://doi.org/10.1186/s11658-024-00533-5
https://hal.science/hal-04428031

2023

Stabilization of luminescent mononuclear three-coordinate cui complexes by two distinct cavity-shaped diphosphanes obtained from a single α-cyclodextrin precursor
Phan T.-A., Jouffroy M., Matt D., Armaroli N., Saavedra Moncada A., Bandini E., Delavaux-Nicot B., Nierengarten J.-F., Armspach D.
Chemistry – A European Journal 2023, e202302750/1-9.
https://doi.org/10.1002/chem.202302750
https://hal.science/hal-04322174

Phenyl dialkynylcarbinols, a bioinspired series of synthetic antitumor acetylenic lipids
Bossuat M., Rullière P., Preuilh N., Peixoto A., Joly E., Gomez J.-G., Bourkhis M., Rodriguez F., Gonçalves F., Fabing I., Gaspard H., Bernardes-Génisson V., Maraval V., Ballereau S., Chauvin R., Britton S., Génisson Y.
Journal of Medicinal Chemistry 2023, 66(20), 13918-13945.
https://doi.org/10.1021/acs.jmedchem.3c00859
https://hal.science/hal-04273137

“Click” chemistry for the functionalization of graphene oxide with phosphorus dendrons: Synthesis, characterization and preliminary biological properties
Alami O., Laurent R., Tassé M., Coppel Y., Bignon J., El Kazzouli S., Majoral J.-P., El Brahmi N., Caminade A.-M.
Chemistry – A European Journal 2023, 29(66), e202302198/1-10.
https://doi.org/10.1002/chem.202302198
https://hal.science/hal-04269848

Functionalization of graphene oxide surfaces with phosphorus dendrimer and dendron
Alami O., Laurent R., Tassé M., Coppel Y., Collière V., Bignon J., Majoral J.-P., El Kazzouli S., El Brahmi N., Caminade A.-M.
FlatChem 2023, 42, 100564/1-12.
https://doi.org/10.1016/j.flatc.2023.100564
https://hal.science/hal-04268533

The Ubiquitin Code
Rodriguez M. S., Bario R. (Eds). Springer: New York, 2023. (978-1-0716-2858-4).
http://dx.doi.org/10.1007/978-1-0716-2859-1
https://hal.science/hal-04269638

Isolation and Mass Spectrometry Identification of K48 and K63 Ubiquitin Proteome Using Chain-Specific Nanobodies
Gonzalez-Santamarta M., Ceccato L., Carvalho A. S., Rain J.-C., Matthiesen R., Rodriguez M. S.
in Methods in Molecular Biology The Ubiquitin Code, M. S. Rodriguez, R. Barrio (Eds). Springer: New York, 2023, pp. 125-136. (978-1-0716-2859-1).
https://doi.org/10.1007/978-1-0716-2859-1_9
https://hal.science/hal-04269347

A Computational Tool for Analysis of Mass Spectrometry Data of Ubiquitin-Enriched Samples
Matthiesen R., Rodriguez M. S., Carvalho A. S.
in Methods in Molecular Biology The Ubiquitin Code, M. S. Rodriguez, R. Barrio (Eds). Springer: New York, 2023, pp. 205-214. (978-1-0716-2859-1).
https://doi.org/10.1007/978-1-0716-2859-1_15
https://hal.science/hal-04269366

Analysis of ATG8 Family Members Using LC3-Interacting Regions (LIR)-Based Molecular Traps
Quinet G., Génin P., Belgareh-Touzé N., Ozturk O., Weil R., Cohen M. M., Legouis R., Rodriguez M. S.
in Methods in Molecular Biology. The Ubiquitin Code, M. S. Rodriguez, R. Barrio (Eds). Springer: New York, 2023, pp. 191-204. (978-1-0716-2859-1).
https://doi.org/10.1007/978-1-0716-2859-1_14
https://hal.science/hal-03991599

Alkyl chains impact in polymer-based organic solar cells
Moineau-Chane Ching K. I.
Encyclopedia Platform. Bâle (Switzerland), 2023, Entry 49374.
https://encyclopedia.pub/entry/49374
https://hal.science/hal-04211180

Impact of alkyl-based side chains in conjugated materials for bulk heterojunction organic photovoltaic cells-A review
Moineau-Chane Ching K. I.
Energies 2023, 16(18), 6639.
https://doi.org/10.3390/en16186639
https://hal.science/hal-04209579

Dendritic structures functionalized with boron clusters, in particular carboranes, and their biological properties
Caminade A.-M., Milewski M., Hey-Hawkins E.
Pharmaceutics 2023, 15(8), 2117/1-29.
https://doi.org/10.3390/pharmaceutics15082117
https://hal.science/hal-04195212

Interaction of phosphorus dendrimers with pre-existing metal nanoparticles
Caminade A.-M.
Encyclopedia Platform. Bâle (Switzerland), 2023, Entry 47635.
https://encyclopedia.pub/entry/47635
https://hal.science/hal-04195444

Phosphorus dendrimers for the synthesis of metal nanoparticles
Caminade A.-M.
Encyclopedia Platform. Bâle (Switzerland), 2023, Entry 47977.
https://encyclopedia.pub/entry/47977
https://hal.science/hal-04195529

Pitfalls of a structure determination: The structure of closo-9-[4-(dibenzylamino)phenyl]-1,2-dicarbadodecaborane(12)
Milewski M., Caminade A.-M., Hey-Hawkins E., Lonnecke P.
in Modern approaches and tools for teaching crystallography, G. Diaz de Delgado, S. Parkin (Eds). IUCr: Chester 2023, Art. 6 (Issu de Acta Crystallographica 2022, E78, pp. 1145-1150).
https://journals.iucr.org/special_issues/2023/teaching/
https://doi.org/10.1107/S205698902201043X
https://hal.science/hal-04195359

Phosphorus dendrimers for metal-free ligation: Design of multivalent pharmacological chaperones against Gaucher disease
Tran M. L., Borie-Guichot M., Garcia V., Oukhrib A., Génisson Y., Levade T., Ballereau S., Turrin C. O., Dehoux C.
Chemistry – A European Journal 2023, 29(53), e202301210/1-9.
https://doi.org/10.1002/chem.202301210
https://hal.science/hal-04175496

Interplay between nanoparticles and phosphorus dendrimers, and their properties
Caminade A.-M.
Molecules 2023, 28(15), 5739/1-22.
https://doi.org/10.3390/molecules28155739
https://hal.science/hal-04174099

Strategies for the preparation of phosphorus Janus dendrimers
Cejas-Sánchez J., Kajetanowicz A., Grela K., Caminade A.-M., Sebastían Perez R. M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2023, Entry 47345.
https://encyclopedia.pub/entry/47345
https://hal.science/hal-04174119

Strategies for the preparation of phosphorus Janus dendrimers and their properties
Cejas-Sánchez J., Kajetanowicz A., Grela K., Caminade A.-M., Sebastián R. M.
Molecules 2023, 28(14), 5570/1-18.
https://doi.org/10.3390/molecules28145570
https://hal.science/hal-04169247

Tuning the photoluminescence properties of SLE- and MRL-active tricarbonylrhenium(I) complexes through minor structural changes of the organic ligand
Poirot A., Leygue N., Delavaux-Nicot B., Saffon-Merceron N., Allain C., Benoist E., Fery-Forgues S.
Journal of Photochemistry and Photobiology A: Chemistry 2023, 445, 114982.
https://doi.org/10.1016/j.jphotochem.2023.114982
https://hal.science/hal-04158433

Low-generation cationic phosphorus dendrimers: Novel approach to tackle drug-resistant S. aureus in vitro and in vivo
Apartsin E., Akhir A., Kaul G., Saxena D., Laurent R., Srivastava K. K., Mignani S., Majoral J.-P., Chopra S.
Biomacromolecules 2023, 24(7), 3215-3227.
https://doi.org/10.1021/acs.biomac.3c00266
https://hal.science/hal-04174818

Expanding chitosan reticular chemistry using multifunctional and thermally stable phosphorus-containing dendrimers
Blilid S., Boundor M., Katir N., El Achaby M., Lahcini M., Majoral J.-P., Bousmina M., El Kadib A.
Macromolecules 2023, 56(3), 1223-1235.
https://doi.org/10.1021/acs.macromol.2c02358
https://hal.science/hal-04174850

Useful synthetic pathways to original, stable tunable neutral and anionic phosphorus dendrimers: new opportunities to expand dendrimer space
Karpus A., Mignani S., Apartsin E., Zablocka M., Shi X., Majoral J.-P.
New Journal of Chemistry 2023, 47(5), 2474-2478.
http://dx.doi.org/10.1039/D2NJ05157E
https://hal.science/hal-04174881

Effects of dendrimer-microRNA nanoformulations against glioblastoma stem cells
Knauer N., Meschaninova M., Muhammad S., Hänggi D., Majoral J.-P., Kahlert U. D., Kozlov V., Apartsin E. K.
Pharmaceutics 2023, 15(3), 968/1-19.
https://doi.org/10.3390/pharmaceutics15030968
https://hal.science/hal-04174917

Effects of cationic dendrimers and their complexes with microRNAs on immunocompetent cells
Knauer N., Pashkina E., Aktanova A., Boeva O., Arkhipova V., Barkovskaya M., Meschaninova M., Karpus A., Majoral J.-P., Kozlov V., Apartsin E.
Pharmaceutics 2023, 15(1), 148/1-16.
https://doi.org/10.3390/pharmaceutics15010148
https://hal.science/hal-04174971

Cationic phosphorus dendron nanomicelles deliver microRNA mimics and microRNA inhibitors for enhanced anti-inflammatory therapy of acute lung injury
Li J., Chen L., Sun H., Zhan M., Laurent R., Mignani S., Majoral J.-P., Shen M., Shi X.
Biomaterials Science 2023, 11(4), 1530-1539.
http://dx.doi.org/10.1039/D2BM01807A
https://hal.science/hal-04175366

Endocannabinoid degradation enzyme inhibitors as potential antipsychotics: A medicinal chemistry perspective
Mangiatordi G. F., Cavalluzzi M. M., Delre P., Lamanna G., Lumuscio M. C., Saviano M., Majoral J.-P., Mignani S., Duranti A., Lentini G.
Biomedicines 2023, 11(2), 469/1-18.
https://doi.org/10.3390/biomedicines11020469
https://hal.science/hal-04174953

Effect of amphiphilic phosphorous dendrons on the conformation, secondary structure, and zeta potential of albumin and thrombin
Terehova M., Magiera J., Qiu J., Majoral J.-P., Shi X., Mignani S., Ionov M., Waczulikova I., Bryszewska M., Shcharbin D.
Polymer Bulletin 2023, 80(8), 9181-9193.
https://doi.org/10.1007/s00289-022-04512-8
https://hal.science/hal-04174803

Amphiphilic phosphorus dendrons associated with anti-inflammatory siRNA reduce symptoms in murine collagen-induced arthritis
Yu Z., Tsapis N., Fay F., Chen L., Karpus A., Shi X., Cailleau C., García Pérez S., Huang N., Vergnaud J., Mignani S., Majoral J.-P., Fattal E.
Biomacromolecules 2023, 24(2), 667-677.
https://doi.org/10.1021/acs.biomac.2c01117
https://hal.science/hal-04101289v1

Phosphorous dendron micelles as a nanomedicine platform for cooperative tumor chemoimmunotherapy via synergistic modulation of immune cells
Zhan M., Qiu J., Fan Y., Chen L., Guo Y., Wang Z., Li J., Majoral J.-P., Shi X.
Advanced Materials 2023, 35(3), 2208277/1-17.
https://doi.org/10.1002/adma.202208277
https://hal.science/hal-04174870

LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans
Leboutet R., Largeau C., Müller L., Prigent M., Quinet G., Rodriguez M. S., Cuif M.-H., Hoppe T., Culetto E., Lefebvre C., Legouis R.
eLife 2023, 12e85748.
https://doi.org/10.7554/eLife.85748
https://hal.science/hal-04157249

Amphiphilic phosphorous dendron micelles co-deliver microRNA inhibitor and doxorubicin for augmented triple negative breast cancer therapy
Chen L., Zhan M., Li J., Cao L., Sun H., Laurent R., Mignani S., Caminade A.-M., Majoral J.-P., Shi X.
Journal of Materials Chemistry B 2023, 11 (24), 5483-5493.
http://dx.doi.org/10.1039/D2TB02114E
https://hal.science/hal-04144460

Fluorescent groups at the core of phosphorus dendrons and their properties
Caminade A.-M., Hameau A., Moineau-Chane Ching K., Turrin C.-O.
Helvetica Chimica Acta 2023, 106, e202300048/1-13.
https://doi.org/10.1002/hlca.202300048
https://hal.science/hal-04121917

Pillar[5]arene-porphyrin conjugates: from molecular flowers to photoactive rotaxanes
Nierengarten I., Hahn U., Holler M., Delavaux-Nicot B., Maisonhaute E., Nierengarten J.-F.
Journal of Porphyrins and Phthalocyanines 2023, 27(01n04), 47-54.
https://doi.org/10.1142/s1088424623500384
https://hal.science/hal-04087240

The chemistry of P=N−P=X (X=S, O, NR) linkages for the synthesis of dendritic structures
Maraval V., Laurent R., Caminade A.-M.
ChemPlusChem 2023, 88(4), e202300064/1-23.
https://doi.org/10.1002/cplu.202300064
https://hal.science/hal-04064179

Personalized and Precision Medicine 2022
Caminade A.-M. (Ed.)
MDPI: Bâle, 2023. 272 p. (978-3-036-57045-7 ).
https://doi.org/10.3390/books978-3-0365-7044-0
https://hal.science/hal-04058706

Phosphorus dendrimers as physical hydrogels and their properties
Apartsin E., Caminade A.-M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2023, Entry 41022.
https://encyclopedia.pub/entry/41022
https://hal.science/hal-04039186

Using a diphenyl-bi-(1,2,4-triazole) tricarbonylrhenium(i) complex with intramolecular π–π stacking interaction for efficient solid-state luminescence enhancement
Poirot A., Vanucci-Bacqué C., Delavaux-Nicot B., Meslien C., Saffon-Merceron N., Serpentini C.-L., Bedos-Belval F., Benoist E., Fery-Forgues S.
Dalton Transactions 2023, 52(17), 5453-5465.
http://dx.doi.org/10.1039/D2DT03573A
https://hal.science/hal-04023657

Editorial, Personalized and Precision Medicine 2022
Caminade A.-M.
Journal of Personalized Medicine 2023, 13(3), 459/1-4.
https://doi.org/10.3390/jpm13030459
https://hal.science/hal-04009399

Stable luminescent [Cu(NN)(PP)]+ complexes incorporating a β-cyclodextrin-based diphosphane ligand with metal-confining properties
Phan T.-A., Armaroli N., Saavedra Moncada A., Bandini E., Delavaux-Nicot B., Nierengarten J.-F., Armspach D.
Angewandte Chemie, International Edition 2023, 62(6), e202214638/1-7.
https://doi.org/10.1002/anie.202214638
https://hal.science/hal-03962970

Single-component physical hydrogels of dendritic molecules
Apartsin E., Caminade A.-M.
Journal of Composites Science 2023, 7(1), 26/1-19.
https://doi.org/10.3390/jcs7010026
https://hal.science/hal-03932728

Luminescent fac-[ReX(CO)3(phenyl-pyta)] (X = Cl, Br, I) complexes: influence of the halide ligand on the electronic properties in solution and in the solid state
Poirot A., Vanucci-Bacqué C., Delavaux-Nicot B., Saffon-Merceron N., Serpentini C.-L., Leygue N., Bedos-Belval F., Benoist E., Fery-Forgues S.
Photochemical & Photobiological Sciences 2023, 22, 169-184.
https://doi.org/10.1007/s43630-022-00307-y
https://hal.archives-ouvertes.fr/hal-03807853

 

2022

Ubiquitin-chains dynamics and its role regulating crucial cellular processes
Gonzalez-Santamarta M., Bouvier C., Rodriguez M. S., Xolalpa W.
Seminars in Cell & Developmental Biology 2022, 132, 155-170.
https://doi.org/10.1016/j.semcdb.2021.11.023
https://hal.science/hal-04038730

Liquid-crystalline order in the phosphorus-containing dendrimers
Furer V. L., Vandyukov A. E., Majoral J.-P., Caminade A.-M., Kovalenko V. I.
Molecules 2022, 27(23), 8214/1-10.
https://doi.org/10.3390/molecules27238214
https://hal.archives-ouvertes.fr/hal-03888217

Modulation of macrophages using nanoformulations with curcumin to treat inflammatory diseases: A concise review
Sun H., Zhan M., Mignani S., Shcharbin D., Majoral J.-P., Rodrigues J., Shi X., Shen M.
Pharmaceutics 2022, 14(10), 2239/1-25.
https://doi.org/10.3390/pharmaceutics14102239
https://hal.archives-ouvertes.fr/hal-03888405

Pitfalls of a structure determination: The structure of closo-9-[4-(dibenzylamino)phenyl]-1,2-dicarbadodecaborane(12)
Milewski M., Caminade A.-M., Hey-Hawkins E., Lonnecke P.
Acta Crystallographica Section E 2022, 78(12), 1145-1150.
https://doi.org/10.1107/S205698902201043X
https://hal.archives-ouvertes.fr/hal-03875823

Chemotherapy mediated by biomimetic polymeric nanoparticles potentiates enhanced tumor immunotherapy via amplification of endoplasmic reticulum stress and mitochondrial dysfunction
Guo Y., Fan Y., Wang Z., Li G., Zhan M., Gong J., Majoral J.-P., Shi X., Shen M.
Advanced Materials 2022, 34(42), 2206861/1-18.
https://doi.org/10.1002/adma.202206861
https://hal.archives-ouvertes.fr/hal-03807818

Dendrimers in personalized medicine
Caminade A.-M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2022, Entry 27135.
https://encyclopedia.pub/entry/27135
https://hal.archives-ouvertes.fr/hal-03789551

Specific bifunctionalization on the phosphorus dendrimers
Petriccone M., Laurent R., Turrin C.-O., Sebastián R. M., Caminade A.-M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2022, Entry 26972.
https://encyclopedia.pub/entry/26972
https://hal.archives-ouvertes.fr/hal-03789588

Dendrimers, an emerging opportunity in personalized medicine?
Caminade A.-M.
Journal of Personalized Medicine 2022, 12(8), 1334/1-12.
https://doi.org/10.3390/jpm12081334
https://hal.archives-ouvertes.fr/hal-03760309

Specific bifunctionalization on the surface of phosphorus dendrimers syntheses and properties
Petriccone M., Laurent R., Turrin C.-O., Sebastián R. M., Caminade A.-M.
Organics 2022, 3(3), 240-261.
https://doi.org/10.3390/org3030018
https://hal.archives-ouvertes.fr/hal-03744649

Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury
Li J., Chen L., Li C., Fan Y., Zhan M., Sun H., Mignani S., Majoral J.-P., Shen M., Shi X.
Theranostics 2022, 12(7), 3407-3419.
https://doi.org/10.7150/thno.70701
https://hal.archives-ouvertes.fr/hal-03807996

In vitro interactions of amphiphilic phosphorous dendrons with liposomes and exosomes-implications for blood viscosity changes
Veliskova M., Zvarik M., Suty S., Jacko J., Mydla P., Cechova K., Dzubinska D., Morvova M., Ionov M., Terehova M., Majoral J.-P., Bryszewska M., Waczulikova I.
Pharmaceutics 2022, 14(8), 1596/1-17.
https://doi.org/10.3390/pharmaceutics14081596
https://hal.archives-ouvertes.fr/hal-03808033

Synthesis of ferrocenyl phosphorhydrazone dendrimers
Caminade A.-M., Manoury E.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2022, Entry 23675.
https://encyclopedia.pub/entry/23675
https://hal.archives-ouvertes.fr/hal-03714158

Engineered stable bioactive per se amphiphilic phosphorus dendron nanomicelles as a highly efficient drug delivery system to take down breast cancer in vivo
Chen L., Cao L., Zhan M., Li J., Wang D., Laurent R., Mignani S., Caminade A.-M., Majoral J.-P., Shi X.
Biomacromolecules 2022, 23(7), 2827-2837.
https://doi.org/10.1021/acs.biomac.2c00197
https://hal.archives-ouvertes.fr/hal-03725719

Curing inflammatory diseases using phosphorous dendrimers
Caminade A.-M., Turrin C.-O., Poupot R.
WIREs Nanomedicine and Nanobiotechnology 2022, e1783/1-22.
https://doi.org/10.1002/wnan.1783
https://hal.archives-ouvertes.fr/hal-03597831

In vitro validation of the therapeutic potential of dendrimer-based nanoformulations against tumor stem cells
Knauer N., Arkhipova V., Li G., Hewera M., Pashkina E., Nguyen P.-H., Meschaninova M., Kozlov V., Zhang W., Croner R. S., Caminade A.-M., Majoral J.-P., Apartsin E. K., Kahlert U. D.
International Journal of Molecular Sciences 2022, 23(10), 5691/1-18.
https://doi.org/10.3390/ijms23105691
https://hal.archives-ouvertes.fr/hal-03694847

Triazine-carbosilane dendrimersomes enhance cellular uptake and phototoxic activity of rose Bengal in Basal cell skin carcinoma cells
Sztandera K., Gorzkiewicz M., Bątal M., Arkhipova V., Knauer N., Sánchez-Nieves J., de la Mata F. J., Gómez R., Apartsin E., Klajnert-Maculewicz B.
International Journal of Nanomedicine 2022, 17, 1139-1154.
https://doi.org/10.2147/ijn.s352349
https://hal.archives-ouvertes.fr/hal-03669929

Constitutive activation of p62/sequestosome-1-mediated proteaphagy regulates proteolysis and impairs cell death in bortezomib-resistant mantle cell lymphoma
Quinet G., Xolalpa W., Reyes-Garau D., Profitós-Pelejà N., Azkargorta M., Ceccato L., Gonzalez-Santamarta M., Marsal M., Andilla J., Aillet F., Bosch F., Elortza F., Loza-Alvarez P., Sola B., Coux O., Matthiesen R., Roué G., Rodriguez M. S.
Cancers 2022, 14(4), 923/1-20.
https://doi.org/10.3390/cancers14040923
https://hal.archives-ouvertes.fr/hal-03648305

Exploring selective autophagy events in multiple biologic models using LC3-interacting regions (LIR)-based molecular traps
Quinet G., Génin P., Ozturk O., Belgareh-Touzé N., Courtot L., Legouis R., Weil R., Cohen M. M., Rodriguez M. S.
Scientific Reports 2022, 12(1), 7652/1-12.
https://doi.org/10.1038/s41598-022-11417-z
https://hal.archives-ouvertes.fr/hal-03666597

Engineered neutral phosphorous dendrimers protect mouse cortical neurons and brain organoids from excitotoxic death
Posadas I., Romero-Castillo L., Ronca R.-A., Karpus A., Mignani S., Majoral J.-P., Muñoz-Fernández M., Ceña V.
International Journal of Molecular Sciences 2022, 23(8), 4391/1-16.
https://doi.org/10.3390/ijms23084391
https://hal.archives-ouvertes.fr/hal-03659072

Dendrimer nanoplatforms for veterinary medicine applications: A concise overview
Mignani S., Shi X., Rodrigues J., Tomás H., Majoral J.-P.
Drug Discovery Today 2022, 27(5), 1251-1260.
https://doi.org/10.1016/j.drudis.2022.01.001
https://hal.archives-ouvertes.fr/hal-03659120

Engineered phosphorus dendrimers as powerful non-viral nanoplatforms for gene delivery: A great hope for the future of cancer therapeutics
Mignani S., Shi X., Bryszewska M., Shcharbin D., Majoral J.-P.
Exploration of Targeted Anti-tumor Therapy 2022, 3(1), 50-61.
https://doi.org/10.37349/etat.2022.00071
https://hal.archives-ouvertes.fr/hal-03659099

Crown macromolecular derivatives: Stepwise design of new types of polyfunctionalized phosphorus dendrimers
Karpus A., Mignani S., Zablocka M., Majoral J.-P.
The Journal of Organic Chemistry 2022, 87(5), 3433-3441.
https://doi.org/10.1021/acs.joc.1c03009
https://hal.archives-ouvertes.fr/hal-03659036

PEG-cored phosphorus dendrimers: Synthesis and functionalization
Dib H., Rebière J., Rebout C., Alami O., El Kazzouli S., El Brahmi N., Laurent R., Delavaux-Nicot B., Caminade A.-M.
Results in Chemistry 2022, 4, 100304/1-10.
https://doi.org/10.1016/j.rechem.2022.100304
https://hal.archives-ouvertes.fr/hal-03578838

Amphiphilic triazine-phosphorus metallodendrons possessing anti-cancer stem cell activity
Apartsin E. K., Knauer N., Kahlert U. D., Caminade A.-M.
Pharmaceutics 2022, 14(2), 393/1-13.
https://doi.org/10.3390/pharmaceutics14020393
https://hal.archives-ouvertes.fr/hal-03660604

Dendriplex-impregnated hydrogels with programmed release rate
Apartsin E., Venyaminova A., Majoral J.-P., Caminade A.-M.
Frontiers in Chemistry 2022, 9, 780608/1-7.
https://doi.org/10.3389/fchem.2021.780608
https://hal.archives-ouvertes.fr/hal-03547654

2021

AB5 derivatives of cyclotriphosphazene
Caminade A.-M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2021, Entry 12744.
https://encyclopedia.pub/entry/12744
https://hal.archives-ouvertes.fr/hal-03714118

AB5 derivatives of cyclotriphosphazene for the synthesis of dendrons and their applications
Zibarov A., Oukhrib A., Aujard Catot J., Turrin C.-O., Caminade A.-M.
Molecules 2021, 26(13), 4017/1-24.
https://doi.org/10.3390/molecules26134017
https://hal.archives-ouvertes.fr/hal-03378292

Fluctuations in AKT and PTEN activity are linked by the E3 ubiquitin ligase cCBL
Olazábal-Morán M., Sánchez-Ortega M., Martínez-Muñoz L., Hernández C., Rodríguez M. S., Mellado M., Carrera A. C.
Cells 2021, 10(11), 2803/1-21.
https://doi.org/10.3390/cells10112803
https://hal.archives-ouvertes.fr/hal-03728095

Impact of molecular rigidity on the gene delivery efficiency of core–shell tecto dendrimers
Wang D., Chen L., Gao Y., Song C., Ouyang Z., Li C., Mignani S., Majoral J.-P., Shi X., Shen M.
Journal of Materials Chemistry B 2021, 9(31), 6149-6154.
http://dx.doi.org/10.1039/D1TB01328A
https://hal.archives-ouvertes.fr/hal-03658965

Dendrimers functionalized with palladium complexes of N-, N,N-, and N,N,N-ligands
Vanbellingen Q., Servin P., Coinaud A., Mallet-Ladeira S., Laurent R., Caminade A.-M.
Molecules 2021, 26(8), 2333/1-19.
https://doi.org/10.3390/molecules26082333
https://hal.archives-ouvertes.fr/hal-03275902

Comparison of the effects of dendrimer, micelle and silver nanoparticles on phospholipase A2 structure
Terehova M., Dzmitruk V., Abashkin V., Kirakosyan G., Ghukasyan G., Bryszewska M., Pedziwiatr-Werbicka E., Ionov M., Gómez R., de la Mata F. J., Mignani S., Shi X., Majoral J.-P., Sukhodola A., Shcharbin D.
Journal of Biotechnology 2021, 331, 48-52.
https://doi.org/10.1016/j.jbiotec.2021.03.009
https://hal.archives-ouvertes.fr/hal-03245002

Blood compatibility of amphiphilic phosphorous dendrons—prospective drug nanocarriers
Suty S., Oravczova V., Garaiova Z., Subjakova V., Ionov M., Shcharbin D., Simonikova Z., Bartek P., Zvarik M., Shi X., Mignani S., Majoral J.-P., Bryszewska M., Hianik T., Waczulikova I.
Biomedicines 2021, 9(11), 1672/1-13.
https://doi.org/10.3390/biomedicines9111672
https://hal.archives-ouvertes.fr/hal-03658953

Facile synthesis of amphiphilic fluorescent phosphorus dendron-based micelles as antiproliferative agents: First investigations
Qiu J., Chen L., Zhan M., Laurent R., Bignon J., Mignani S., Shi X., Caminade A.-M., Majoral J.-P.
Bioconjugate Chemistry 2021, 32(2), 339-349.
https://doi.org/10.1021/acs.bioconjchem.0c00716
https://hal.archives-ouvertes.fr/hal-03148744

Phenyl-pyta-tricarbonylrhenium(i) complexes: combining a simplified structure and steric hindrance to modulate the photoluminescence properties
Poirot A., Vanucci-Bacqué C., Delavaux-Nicot B., Leygue N., Saffon-Merceron N., Alary F., Bedos-Belval F., Benoist E., Fery-Forgues S.
Dalton Transactions 2021, 50(39), 13686-13698.
http://dx.doi.org/10.1039/D1DT02161C
https://hal.archives-ouvertes.fr/hal-03358697

Dendrimeric HIV-peptide delivery nanosystem affects lipid membranes structure
Milowska K., Rodacka A., Melikishvili S., Buczkowski A., Pałecz B., Waczulikova I., Hianik T., Majoral J.-P., Ionov M., Bryszewska M.
Scientific Reports 2021, 11(1), 16810/1-12.
https://doi.org/10.1038/s41598-021-96194-x
https://hal.archives-ouvertes.fr/hal-03658931

Safe polycationic dendrimers as potent oral in vivo inhibitors of Mycobacterium tuberculosis: A new therapy to take down tuberculosis
Mignani S., Tripathi V. D., Soam D., Tripathi R. P., Das S., Singh S., Gandikota R., Laurent R., Karpus A., Caminade A.-M., Steinmetz A., Dasgupta A., Srivastava K. K., Majoral J.-P.
Biomacromolecules 2021, 22(6), 2659-2675.
https://doi.org/10.1021/acs.biomac.1c00355
https://hal.archives-ouvertes.fr/hal-03273968

Dendritic macromolecular architectures: Dendrimer-based polyion complex micelles
Mignani S., Shi X., Zablocka M., Majoral J.-P.
Biomacromolecules 2021, 22(2), 262-274.
https://doi.org/10.1021/acs.biomac.0c01645
https://hal.archives-ouvertes.fr/hal-03275792

Multivalent copper(II)-conjugated phosphorus dendrimers with noteworthy in vitro and in vivo antitumor activities: A concise overview
Mignani S., Shi X., Steinmetz A., Majoral J.-P.
Molecular Pharmaceutics 2021, 18(1), 65-73.
https://doi.org/10.1021/acs.molpharmaceut.0c00892
https://hal.archives-ouvertes.fr/hal-03275781

First-in-class and best-in-class dendrimer nanoplatforms from concept to clinic: Lessons learned moving forward
Mignani S., Shi X., Rodrigues J., Tomas H., Karpus A., Majoral J.-P.
European Journal of Medicinal Chemistry 2021, 219, 113456/1-14.
https://doi.org/10.1016/j.ejmech.2021.113456
https://hal.archives-ouvertes.fr/hal-03275575

Non-invasive intranasal administration route directly to the brain using dendrimer nanoplatforms: An opportunity to develop new CNS drugs
Mignani S., Shi X., Karpus A., Majoral J.-P.
European journal of medicinal chemistry 2021, 209, 112905/1-11.
https://doi.org/10.1016/j.ejmech.2020.112905
https://hal.archives-ouvertes.fr/hal-03203309

Functionalized dendrimer platforms as a new forefront arsenal targeting SARS-CoV-2: An opportunity
Mignani S., Shi X., Karpus A., Lentini G., Majoral J.-P.
Pharmaceutics 2021, 13(9), 1513/1-14.
https://doi.org/10.3390/pharmaceutics13091513
https://hal.archives-ouvertes.fr/hal-03657073

Clinical diagonal translation of nanoparticles: Case studies in dendrimer nanomedicine
Mignani S., Shi X., Guidolin K., Zheng G., Karpus A., Majoral J.-P.
Journal of Controlled Release 2021, 337, 356-370.
https://doi.org/10.1016/j.jconrel.2021.07.036
https://hal.archives-ouvertes.fr/hal-03657022

In vivo therapeutic applications of phosphorus dendrimers: state of the art
Mignani S., Shi X., Ceña V., Shcharbin D., Bryszewska M., Majoral J.-P.
Drug Discovery Today 2021, 26(3), 677-689.
https://doi.org/10.1016/j.drudis.2020.11.034
https://hal.archives-ouvertes.fr/hal-03274966

Engineered non-invasive functionalized dendrimer/dendron-entrapped/complexed gold nanoparticles as a novel class of theranostic (radio)pharmaceuticals in cancer therapy
Mignani S., Shi X., Ceña V., Rodrigues J., Tomas H., Majoral J.-P.
Journal of Controlled Release 2021, 332, 346-366.
https://doi.org/10.1016/j.jconrel.2021.03.003
https://hal.archives-ouvertes.fr/hal-03203301

First-in-class phosphorus dendritic framework, a wide surface functional group palette bringing noteworthy anti-cancer and anti-tuberculosis activities: what lessons to learn?
Mignani S., Bignon J., Shi X., Majoral J.-P.
Molecules 2021, 26(12), 3708/1-14.
https://doi.org/10.3390/molecules26123708
https://hal.archives-ouvertes.fr/hal-03656981

Hybrid phosphorus–viologen dendrimers as new soft nanoparticles: design and properties
Majoral J.-P., Zablocka M., Ciepluch K., Milowska K., Bryszewska M., Shcharbin D., Katir N., El Kadib A., Caminade A.-M., Mignani S.
Organic Chemistry Frontiers 2021, 8(16), 4607-4622.
http://dx.doi.org/10.1039/D1QO00511A
https://hal.archives-ouvertes.fr/hal-03275562

Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation
Lobato-Gil S., Heidelberger J. B., Maghames C., Bailly A., Brunello L., Rodriguez M. S., Beli P., Xirodimas D. P.
Cell Reports 2021, 34(3), 108635/1-15.
https://doi.org/10.1016/j.celrep.2020.108635
https://hal.archives-ouvertes.fr/hal-03176206

SALL1 modulates CBX4 stability, nuclear bodies, and regulation of target genes
Giordano I., Pirone L., Muratore V., Landaluze E., Pérez C., Lang V., Garde-Lapido E., Gonzalez-Lopez M., Barroso-Gomila O., Vertegaal A. C. O., Aransay A. M., Rodriguez J. A., Rodriguez M. S., Sutherland J. D., Barrio R.
Frontiers in Cell and Developmental Biology 2021, 9(2610), 715868/1-17.
https://doi.org/10.3389/fcell.2021.715868
https://hal.archives-ouvertes.fr/hal-03370040

SUMOylation modulates the stability and function of PI3K-p110β
El Motiam A., de la Cruz-Herrera C. F., Vidal S., Seoane R., Baz-Martínez M., Bouzaher Y. H., Lecona E., Esteban M., Rodríguez M. S., Vidal A., Collado M., Rivas C.
Cellular and molecular life sciences : CMLS 2021, 78, 4053-4065.
https://doi.org/10.1007/s00018-021-03826-6
https://hal.archives-ouvertes.fr/hal-03203257

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3-ITD-driven acute myeloid leukemia
Lopez-Reyes R. G., Quinet G., Gonzalez-Santamarta M., Larrue C., Sarry J.-E., Rodriguez M. S.
FEBS Open Bio 2021, 11(1), 48-60.
https://doi.org/10.1002/2211-5463.12950
https://hal.archives-ouvertes.fr/hal-03007137

The usefulness of trivalent phosphorus for the synthesis of dendrimers
Caminade A.-M., Moineau-Chane Ching K. I., Delavaux-Nicot B.
Molecules 2021, 26(2), 269/1-30.
https://doi.org/10.3390/molecules26020269
https://hal.archives-ouvertes.fr/hal-03131217

Dendritic metal complexes for bioimaging. Recent advances
Caminade A.-M., Hameau A., Turrin C.-O., Laurent R., Majoral J.-P.
Coordination Chemistry Reviews 2021, 430, 213739/1-27.
https://doi.org/10.1016/j.ccr.2020.213739
https://hal.archives-ouvertes.fr/hal-03131731

Mechanical modulation of the solid-state luminescence of tricarbonyl rhenium(I) complexes through the interplay between two triplet excited states
Calupitan J. P., Poirot A., Wang J., Delavaux-Nicot B., Wolff M., Jaworska M., Métivier R., Benoist E., Allain C., Fery-Forgues S.
Chemistry – A European Journal 2021, 27(12), 4191-4196.
https://doi.org/10.1002/chem.202005245
https://hal.archives-ouvertes.fr/hal-03130077

Electron transfer inside a decaferrocenylated rotaxane analyzed by fast scan cyclic voltammetry and impedance spectroscopy
Boitel-Aullen G., Fillaud L., Huet F., Nierengarten I., Delavaux-Nicot B., Nierengarten J.-.F, Maisonhaute E.
ChemElectroChem 2021, 8(18), 3506-3511.
https://doi.org/10.1002/celc.202100738
https://hal.archives-ouvertes.fr/hal-03292071

Supramolecular self-associations of amphiphilic dendrons and their properties
Apartsin E., Caminade A.-M.
Chemistry – A European Journal 2021, 27(72), 17976-17998.
https://doi.org/10.1002/chem.202102589
https://hal.archives-ouvertes.fr/hal-03547718

Copper complexes of phosphorus dendrimers and their properties
Alami O., Laurent R., Majoral J.-P., El Brahmi N., El Kazzouli S., Caminade A.-M.
Inorganica Chimica Acta 2021, 517, 120212/1-8.
https://doi.org/10.1016/j.ica.2020.120212
https://hal.archives-ouvertes.fr/hal-03131594

Partnerships

Click here to consult the partners
  • Technopolym 

The team is a partner of Technopolym, scientific service of the “Institut de Chimie deToulouse”, specialized in the characterization of polymers and polymer materials: chromatographic studies, characterization of thermal behaviour, physicochemical characterizations, physical and mechanical properties.
Technopolym is by nature open to everyone, academic laboratories or industries.
To contact Technopolym:  ict.technopolym@univ-tlse3.fr
Platform manager : Pascale LABORIE (IGE UPS) (pascale.laborie(at)univ-tlse3.fr)
Scientific referent: Régis LAURENT (regis.laurent(at)lcc-toulouse.fr)
Download Technopolym flyer (.pdf file)

 

  • International Collaborations
    • Germany
      Dietmar Appelhans (Dresden)
      Evamarie Hey-Hawkins (Leipzig)
      Oliver Reiser (Regensburg)
    • Austria
      Wolfgang Knoll (Vienna)
    • Belarus
      Dimitri Shcharbin (Minsk)
    • Canada
      Anton Shakhbazau (Calgary)
    • China
      Xiangyang Shi (Shanghai)
    • South Korea
      Dong Ha Kim (Seoul)
    • Spain
      Rosa Barrio (Bilbao)
      Victorio Cadierno (Oviedo)
      Valentin Cena (Albacete)
      Agusti Lledos (Barcelona)
      Nazario Martin (Madrid)
      Francisco J. de la Mata de la Mata (Alcala de Henares)
      Maria Angeles Munoz-Fernandez (Madrid)
      Enrique Orti (Valencia)
      Anna Pla-Quintana (Girona)
      Niels Reichardt (San Sebastian)
      Carmen Rivas (Santiago de Compostela)
      Antonio Romerosa (Almeria)
      Gaël Roué (Barcelona)
      Rosa Maria Sebastian (Barcelona)
      José Vidal-Gancedo (Barcelona)
    • Italy
      Nicola Armaroli (Bologna)
      Germana Meroni (Trieste)
      Francesca Ottaviani (Urbino)
      Anna Painelli (Parma)
      Maurizio Peruzzini (Firenze)
    • Morocco
      Mosto M. Bousmina (Fes)
      Nabil El Brahmi (Fes)
      Said El Kazzouli (Fes)
      Abdelkrim El Khadid (Fes)
      Mohamed Hajjaji (Marrakech)
    • Mexico
      Ernesto Rivera (Mexico City)
    • Poland
      Maria Bryszewska (Lodz)
      Barbara Klajnert (Lodz)
      Maria Zablocka (Lodz)
    • Portugal
      Rune Matthiesen (Lisbon)
      Joao Rodrigues (Madeira)
    • United Kingdom
      Ronald T. Hay (Dundee)
    • Russia
      Evgeny Apartsin (Novosibirsk)
      Victor Furer (Kazan)
      Valeri Kovalenko (Kazan)
      Daria Novoprashina (Novosibirsk)
  • National collaborations
    Jérôme Bignon (Gif sur Yvette)
    Mireille Blanchard-Desce (Bordeaux)
    Laurence Charles (Marseille)
    Bertrand Donnio (Strasbourg)
    Elias Fattal (Chatenay Malabry)
    Emmanuel Maisonhaute (Paris)
    Oleg Melnyck (Lille)
    Serge Mignani (Paris)
    Jean-François Nierengarten (Strasbourg)
    Armelle Ouali (Montpellier)
    Jean-Christophe Rain (Paris)
    Jean-Pierre Sauvage (Strasbourg)
    Marc Taillefer (Montpellier)
    Jean-Baptiste Verlhac (Bordeaux)
    Dimitris Xirodimas (Montpellier)

 

  • Toulouse collaborations
    Fabienne Alary
    Muriel Blanzat
    Georges Czaplicki
    Suzanne Fery-Forgues
    Jean-Marie François
    Yves Génisson
    Muriel Golzio
    Jérôme Nigou
    François Malecaze
    Eric Manoury (LCC)
    Rémy Poupot
    Karine Reybier-Vuattoux
    Emmanuelle Trévisiol

Funding

Click here to consult the funders
  • H2020-MSCA-ITN-2019 EJD 860322 CCIMC: Coordination Chemistry Inspires Molecular Catalysis
    Deputy Coordinator : Anne-Marie Caminade 2020-2024.
  • ARC Foundation for Cancer Research
    PhD Supervisor: Manuel S. Rodriguez
    Beneficiary : Maria Gonzalez Santamarta (2021-2022)
  • Marie Slodowska Curie Actions UbiCODE: European training network to decipher the Ubiquitin Code (GA 765445)
    Coordinators: Manuel S. Rodriguez, Rosa Barrio (Spain) (2018-2022)
  • Occitanie Region:
    Support to laboratory innovation efforts – UbiPièges
    Coordinator: Manuel S. Rodriguez (2019-2022)
  • Occitanie Region: Reinforcement of European Research projects in collaboration with companies
    Coordinator: Manuel S. Rodriguez (2019-2021)
  • Creation of the China France Joint laboratory for healthcare theranostics (LCC, Donghua University, Shanghai).
    French Coordinators Jean-Pierre Majoral and Serge Mignani
    Chinese Coordinator Prof X. Shi.
  • Euronanomed III project: Nanomedicine for glioblastoma therapy / acronyme NANOGLIO.
    French Coordinator: Jean Pierre Majoral
    Scientific Partner: Anne-Marie Caminade 2019-2022.
  • MSCA IF EUREKA (Marie Slodowska-Curie Action) : Multifunctional dendrimers as vectors of therapeutic siRNA.
    French coordinator: Anne-Marie Caminade 2020-2022.
  • Programme PRC 2019 CNRS-NSCF (France-China): Dendrimers against triple negative breast cancer.
    French coordinator: Anne-Marie Caminade, co-coordinators: Serge Mignani, Jean Pierre Majoral 2019-2021.
  • Programme TOUBKAL (Franco-Marocain) : L’oxyde de graphène et les nanotubes de carbone fonctionnalisés par des dendrons et dendrimères phosphorés pour des applications en oncologie.
    French coordinator: Anne-Marie Caminade 2019-2022.
    Moroccan coordinator: Nabil El Brahmi
  • Contrat Agro Innovation International ENCAPS: Encapsulation and release of active substances by dendrimers.
    Anne-Marie Caminade 2019.
  • Programme de soutien à la recherche SIIRI (Québec, France, Espagne) : Nanomatériaux dendritiques comme vecteurs non-viraux pour la livraison de médicaments et de gènes contre le cancer du sein.
    French partners: Anne-Marie Caminade and Jean-Pierre Majoral 2018-2020.
  • ANR 2017 PRC CE9 SLOW2 : Stereo Laser Writing On Water
    Coordinator: Anne-Marie Caminade 2017-2022.
  • GDR CNRS : Phosphore
    WP3 leader « Molécules bioactives et applications » : Anne-Marie Caminade 2017-2021.
  • China Scholarship Council project: Design and properties of biocompatible phosphorus dendrimers to tackle cancers.
    French coordinator: Jean Pierre Majoral 2016-2019
  • Programme COFECUB CAPES (franco-brésilien) : Développement de nanovecteurs pour le traitement de pathologies du système nerveux central.
    French coordinator: Muriel Blanzat (Toulouse)
    Partner: Cédric-Olivier Turrin 2016-2018.
  • Projet VML : Nouveaux dendrimères polypharmacophoriques pour une stratégie thérapeutique duale innovante contre la maladie de Gaucher.
    Coordinator: Yves Génisson (Toulouse)
    Partner: Cédric-Olivier Turrin 2016-2018.
  • CEFIPRA (France-India) : Préparation de dendrimères phosphorés originaux pour lutter contre la tuberculose pulmonaire.
    French coordinator: Anne-Marie Caminade, co-coordinators: Serge Mignani, Jean Pierre Majoral 2015-2019.
  • Réseau GDRI HC3A : Hetero-elements and Coordination Chemistry: from the Concept to Applications.
    Coordinator: Montserat Gomez (Toulouse).
    Team leader: Anne-Marie Caminade 2015-2022.
  • ANR PRTS TREE-DRUG: Development of a drug-candidate: a phosphorus-based dendrimer with anti-inflammatory and immuno-modulatory properties.
    Coordinator: Rémy Poupot (Toulouse)
    Partner: Cédric-Olivier Turrin 2014-2017.
  • Réseau Marie Curie Actions People International Research Staff Exchange Scheme (PIRSES): NANOGEN EU –Belarus-Russia Network in Nanomaterials-Driven Anti-Cancer gene therapy.
    French coordinator : Jean Pierre Majoral 2014-2016
  • Réseau COST CM1302 SIPs: Smart Inorganic Polymers.
    Coordinator: Evamarie Hey-Hawkins (Germany)
    Leader Working group 2: Anne-Marie Caminade 2013-2017
  • China Schorlarship Council project: Design, synthesis and characterization of new organic semi-conductors for photovoltaics.
    Thesis supervisor : Kathleen Moineau-Chane Ching 2013-2016
  • IDEX Université de Toulouse Programme « Nouveaux Entrants » Aurélien Hameau 2013
  • FRM Chimie pour la Médecine : Recherche du/des récepteur(s) spécifique(s) d’un dendrimère phosphoré, candidat-médicament immuno-modulateur.
    Coordinator: Anne-Marie Caminade 2011-2015
  • ANR Blanc COPPERTREE : Traitement antibiofilm de surface par dépôt multicouches de dendrimères et de nanoparticules de cuivre.
    Coordinator: Cédric-Olivier Turrin 2011-2015.
  • CONACyT Scholarship : Photovoltaïque organique : étude de la morphologie de films minces ; conception, synthèse et étude de petites molécules organiques.
    Thesis supervisor: Kathleen Moineau-Chane Ching 2011-2015
  • Contrat COMUE-Région : Photovoltaique Organique : étude des intéractions electroniques aux interfaces des hétérojonctions organiques.
    Thesis supervisor: Kathleen Moineau-Chane Ching 2011-2015
  • ANR Blanc Click-unclick : Assemblage/désassemblage de systèmes prodrogue innovants grâce à une stratégie de chimie Click-Unclick.
    Coordinator: Oleg Melnyk (Lille)
    Partner: Anne-Marie Caminade 2011-2014
  • ANR RPIB 2011 DENDRI’MS : Traitement de la Sclérose en Plaques par un dendrimère phosphoré immuno-modulateur.
    Coordinator: Rémy Poupot (Toulouse)
    Partner: Anne-Marie Caminade 2011-2014
  • CE FP7 SUDOE Interreg IVB, SOE2/P1/E341 CliNK : Nouveaux protocoles de l’immunothérapie : Production de cellules NK activées pour une utilisation clinique.
    Coordinator: Alberto Anel (Espagne)
    Team leader: Anne-Marie Caminade 2011-2013
  • GDR Electronique Organique N° 3368.
    Coordinator: Lionel Hirsch (Bordeaux)
    Steering committee member: Kathleen Moineau-Chane Ching 2010-2018
  • ANR Blanche Internationale Franco-Allemande DENDSWITCH : Dendrimères modifiables par stimulation. Vers des catalyseurs adaptables.
    French coordinator: Anne-Marie Caminade (Evamarie Hey-Hawkins côté Allemand) 2010-2013
  • ANR Emergence INNO-THER-RA : Les dendrimères phosphorés : Molécules innovantes pour le traitement de la Polyarthrite Rhumatoïde.
    Coordinator: Rémy Poupot (Toulouse)
    Partner: Anne-Marie Caminade 2010-2013
  • EuroNanomed European Innovative RTD project proposals in Nanomedicine DENPEPT HIV: Peptide-associated dendrimers in dendritic cells for the development of new nano-HIV vaccines.
    Coordinator: Maria Angeles Munoz Fernandez (Espagne)
    French coordinator: Jean Pierre Majoral 2010-2012
  • Accord Institut Inanotech (Rabat Morocco) – LCC.
    Coordinator: Jean Pierre Majoral 2009-2014
  • Réseau COST TD0802 Biodendrimers: Biomedical applications of dendrimers.
    Coordinator: Barbara Klajnert (Pologne)
    Jean-Pierre Majoral (MC) Anne-Marie Caminade (MC Substitute) 2009-2013
  • ANR Blanche Internationale Franco-Allemande GLOBUCAT : Environmental friendly homogeneous and heterogeneous catalysis.
    French coordinator: Jean Pierre Majoral (Oliver Reiser Germany) 2009-2012
  • Réseau COST CM0802 PhoSciNet: Phosphorus Science Network.
    Coordinator: Evamarie Hey-Hawkins (Germany)
    Vice-leader Working Group 4: Anne-Marie Caminade 2008-2012.
  • Réseau LIA LCMMF : Laboratoire de Chimie Moléculaire Marocco-Français.
    Coordinator: Jean-Jacques Bonnet (Toulouse)
    Team leader: Anne-Marie Caminade 2008-20155
  • ANR Physique et Chimie du Vivant PCV BIODENDRIDOT : Fluorophores dendritiques à 2 photons pour l’imagerie moléculaire, sub-cellulaire et cellulaire et chez l’animal vivant.
    Coordinator: Anne-Marie Caminade 2007-2010
  • Commission EuropéenneCNRS : Projet OLLA (Organic LED’s for lighting and ICT applications).
    Coordinator: Philips Electronics
    De la préparation de complexes du Cu(I) luminescents à l’auto assemblage de systèmes supramoléculaires complexes.
    Thesis supervisor: Béatrice Delavaux-Nicot 2005-2008.
  • Réseau LEA LTPMM : Laboratoire Trans-Pyrénéen : de la Molécule aux Matériaux.
    Coordinator: Antoine Baceiredo (Toulouse)
    Team leader: Anne-Marie Caminade 2006-2013
  • Contrat IFP (Institut Français du Pétrole)
    Anne-Marie Caminade 2005-2008

LCC

Laboratoire de chimie de coordination du CNRS

205 route de Narbonne, BP 44099
31077 Toulouse cedex 4
France

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