Dendrimers and Heterochemistry (Team M)

LCC

Overview

The “Dendrimers and Heterochemistry” team is interested in the synthesis and original properties of phosphorus-containing dendritic macromolecular architectures, such as dendrimers, dendrons, branched polymers, etc.

These macromolecular objects are the subject of various characterizations, and their properties in the fields of catalysis, materials and biology are of particular attention.

Members of the team

All
Directrice de recherche

CAMINADE Anne-Marie

ALAMI Omar
Doctorant

ALAMI Omar

CDD

AMRI Saber

CDD

APARTSIN Evgeny

Doctorant

AUJARD CATOT Julien

ITA

BARTHES Cécile

Doctorant

BOUVIER Corentin

CDD

COUTELLE-REBUT Clemence

DELAVAUX-NICOT Beatrice
Directrice de recherche

DELAVAUX-NICOT Beatrice

GONZALEZ SANTAMARTA Maria
CDD

GONZALEZ SANTAMARTA Maria

Maître de conférences

HAMEAU Aurelien

CDD

KARPUS Andrii

Chargé de recherche

LAURENT Regis

Etudiant

LI Jin

Directeur de recherche

MAJORAL Jean-Pierre

ITA

MARTIN-MOTHES Emmanuelle

ITA

MENENDEZ Christophe

Etudiant

MICHEL Antoine

Doctorant

MILEWSKI Max

Directrice de recherche

MOINEAU-CHANE CHING Kathleen

Doctorant

PETRICCONE Massimo

Directeur de recherche

RODRIGUEZ Manuel

Directeur de recherche

TURRIN Cedric-Olivier

Doctorant

ZIBAROV Artem

Doctorant

ZOU Yu

No Results Found

Directrice de recherche

CAMINADE Anne-Marie

Doctorant

ALAMI Omar

Email:omar.alami(at)lcc-toulouse.fr

Téléphone:0561333133

CDD

AMRI Saber

:saber.amri(at)lcc-toulouse.fr

:0561333134

CDD

APARTSIN Evgeny

Email:evgeny.apartsin(at)lcc-toulouse.fr

Téléphone:0561333233

Doctorant

AUJARD CATOT Julien

Email:julien.aujard(at)lcc-toulouse.fr

Téléphone:0561333134

ITA

BARTHES Cécile

Après l’obtention d’un BTS chimie et génie chimique en 2003, Cécile Barthes a obtenu plusieurs CDD au sein du CNRS dans des laboratoires tels que le CEMES ou le LHFA ainsi que chez Sanofi –aventis toujours en tant que technicienne de synthèse en recherche dans divers domaines. En 2008, elle a obtenu un poste de technicienne de recherche au LCC. Depuis, elle est impliquée dans plusieurs sujets de recherche au sein de deux équipes. Expertise : Synthèse multi-étapes, génération de carbène, synthèse de complexes, catalyse

Email:cecile.barthes@lcc-toulouse.fr

Téléphone:0561333136

Téléphone 2:0561333172

Bureau:G177 / B227

Doctorant

BOUVIER Corentin

CDD

COUTELLE-REBUT Clemence

Email:clemence.coutelle@lcc-toulouse.fr

Téléphone:0561333133

Directrice de recherche

DELAVAUX-NICOT Beatrice

CDD

GONZALEZ SANTAMARTA Maria

Maître de conférences

HAMEAU Aurelien

Email:aurelien.hameau@lcc-toulouse.fr

Téléphone:0561333233

CDD

KARPUS Andrii

Email:andrii.karpus@lcc-toulouse.fr

Téléphone:0561333185

Chargé de recherche

LAURENT Regis

Etudiant

LI Jin

Email:jin.li@lcc-toulouse.fr

Téléphone:0561333125

Directeur de recherche

MAJORAL Jean-Pierre

ITA

MARTIN-MOTHES Emmanuelle

ITA

MENENDEZ Christophe

Etudiant

MICHEL Antoine

Doctorant

MILEWSKI Max

Directrice de recherche

MOINEAU-CHANE CHING Kathleen

Doctorant

PETRICCONE Massimo

Directeur de recherche

RODRIGUEZ Manuel

Directeur de recherche

TURRIN Cedric-Olivier

Doctorant

ZIBAROV Artem

Email:artem.zibarov@lcc-toulouse.fr

Téléphone:0561333233

Doctorant

ZOU Yu

Email:yu.zou@lcc-toulouse.fr

Téléphone:0561333123

Research topics

Team news

No Results Found

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Publications

2023

Single-component physical hydrogels of dendritic molecules
Apartsin E., Caminade A.-M.
Journal of Composites Science 2023, 7(1), 26/1-19.
https://doi.org/10.3390/jcs7010026
https://hal.science/hal-03932728

Luminescent fac-[ReX(CO)3(phenyl-pyta)] (X = Cl, Br, I) complexes: influence of the halide ligand on the electronic properties in solution and in the solid state
Poirot A., Vanucci-Bacqué C., Delavaux-Nicot B., Saffon-Merceron N., Serpentini C.-L., Leygue N., Bedos-Belval F., Benoist E., Fery-Forgues S.
Photochemical & Photobiological Sciences 2023, 22, 169-184.
https://doi.org/10.1007/s43630-022-00307-y
https://hal.archives-ouvertes.fr/hal-03807853

 

2022

Liquid-crystalline order in the phosphorus-containing dendrimers
Furer V. L., Vandyukov A. E., Majoral J.-P., Caminade A.-M., Kovalenko V. I.
Molecules 2022, 27(23), 8214/1-10.
https://doi.org/10.3390/molecules27238214
https://hal.archives-ouvertes.fr/hal-03888217

Modulation of macrophages using nanoformulations with curcumin to treat inflammatory diseases: A concise review
Sun H., Zhan M., Mignani S., Shcharbin D., Majoral J.-P., Rodrigues J., Shi X., Shen M.
Pharmaceutics 2022, 14(10), 2239/1-25.
https://doi.org/10.3390/pharmaceutics14102239
https://hal.archives-ouvertes.fr/hal-03888405

Pitfalls of a structure determination: The structure of closo-9-[4-(dibenzylamino)phenyl]-1,2-dicarbadodecaborane(12)
Milewski M., Caminade A.-M., Hey-Hawkins E., Lonnecke P.
Acta Crystallographica Section E 2022, 78(12), 1145-1150.
https://doi.org/10.1107/S205698902201043X
https://hal.archives-ouvertes.fr/hal-03875823

Chemotherapy mediated by biomimetic polymeric nanoparticles potentiates enhanced tumor immunotherapy via amplification of endoplasmic reticulum stress and mitochondrial dysfunction
Guo Y., Fan Y., Wang Z., Li G., Zhan M., Gong J., Majoral J.-P., Shi X., Shen M.
Advanced Materials 2022, 34(42), 2206861/1-18.
https://doi.org/10.1002/adma.202206861
https://hal.archives-ouvertes.fr/hal-03807818

Dendrimers in personalized medicine
Caminade A.-M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2022, Entry 27135.
https://encyclopedia.pub/entry/27135
https://hal.archives-ouvertes.fr/hal-03789551

Specific bifunctionalization on the phosphorus dendrimers
Petriccone M., Laurent R., Turrin C.-O., Sebastián R. M., Caminade A.-M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2022, Entry 26972.
https://encyclopedia.pub/entry/26972
https://hal.archives-ouvertes.fr/hal-03789588

Dendrimers, an emerging opportunity in personalized medicine?
Caminade A.-M.
Journal of Personalized Medicine 2022, 12(8), 1334/1-12.
https://doi.org/10.3390/jpm12081334
https://hal.archives-ouvertes.fr/hal-03760309

Specific bifunctionalization on the surface of phosphorus dendrimers syntheses and properties
Petriccone M., Laurent R., Turrin C.-O., Sebastián R. M., Caminade A.-M.
Organics 2022, 3(3), 240-261.
https://doi.org/10.3390/org3030018
https://hal.archives-ouvertes.fr/hal-03744649

Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury
Li J., Chen L., Li C., Fan Y., Zhan M., Sun H., Mignani S., Majoral J.-P., Shen M., Shi X.
Theranostics 2022, 12(7), 3407-3419.
https://doi.org/10.7150/thno.70701
https://hal.archives-ouvertes.fr/hal-03807996

In vitro interactions of amphiphilic phosphorous dendrons with liposomes and exosomes-implications for blood viscosity changes
Veliskova M., Zvarik M., Suty S., Jacko J., Mydla P., Cechova K., Dzubinska D., Morvova M., Ionov M., Terehova M., Majoral J.-P., Bryszewska M., Waczulikova I.
Pharmaceutics 2022, 14(8), 1596/1-17.
https://doi.org/10.3390/pharmaceutics14081596
https://hal.archives-ouvertes.fr/hal-03808033

Synthesis of ferrocenyl phosphorhydrazone dendrimers
Caminade A.-M., Manoury E.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2022, Entry 23675.
https://encyclopedia.pub/entry/23675
https://hal.archives-ouvertes.fr/hal-03714158

Engineered stable bioactive per se amphiphilic phosphorus dendron nanomicelles as a highly efficient drug delivery system to take down breast cancer in vivo
Chen L., Cao L., Zhan M., Li J., Wang D., Laurent R., Mignani S., Caminade A.-M., Majoral J.-P., Shi X.
Biomacromolecules 2022, 23(7), 2827-2837.
https://doi.org/10.1021/acs.biomac.2c00197
https://hal.archives-ouvertes.fr/hal-03725719

Curing inflammatory diseases using phosphorous dendrimers
Caminade A.-M., Turrin C.-O., Poupot R.
WIREs Nanomedicine and Nanobiotechnology 2022, e1783/1-22.
https://doi.org/10.1002/wnan.1783
https://hal.archives-ouvertes.fr/hal-03597831

In vitro validation of the therapeutic potential of dendrimer-based nanoformulations against tumor stem cells
Knauer N., Arkhipova V., Li G., Hewera M., Pashkina E., Nguyen P.-H., Meschaninova M., Kozlov V., Zhang W., Croner R. S., Caminade A.-M., Majoral J.-P., Apartsin E. K., Kahlert U. D.
International Journal of Molecular Sciences 2022, 23(10), 5691/1-18.
https://doi.org/10.3390/ijms23105691
https://hal.archives-ouvertes.fr/hal-03694847

Triazine-carbosilane dendrimersomes enhance cellular uptake and phototoxic activity of rose Bengal in Basal cell skin carcinoma cells
Sztandera K., Gorzkiewicz M., Bątal M., Arkhipova V., Knauer N., Sánchez-Nieves J., de la Mata F. J., Gómez R., Apartsin E., Klajnert-Maculewicz B.
International Journal of Nanomedicine 2022, 17, 1139-1154.
https://doi.org/10.2147/ijn.s352349
https://hal.archives-ouvertes.fr/hal-03669929

Constitutive activation of p62/sequestosome-1-mediated proteaphagy regulates proteolysis and impairs cell death in bortezomib-resistant mantle cell lymphoma
Quinet G., Xolalpa W., Reyes-Garau D., Profitós-Pelejà N., Azkargorta M., Ceccato L., Gonzalez-Santamarta M., Marsal M., Andilla J., Aillet F., Bosch F., Elortza F., Loza-Alvarez P., Sola B., Coux O., Matthiesen R., Roué G., Rodriguez M. S.
Cancers 2022, 14(4), 923/1-20.
https://doi.org/10.3390/cancers14040923
https://hal.archives-ouvertes.fr/hal-03648305

Exploring selective autophagy events in multiple biologic models using LC3-interacting regions (LIR)-based molecular traps
Quinet G., Génin P., Ozturk O., Belgareh-Touzé N., Courtot L., Legouis R., Weil R., Cohen M. M., Rodriguez M. S.
Scientific Reports 2022, 12(1), 7652/1-12.
https://doi.org/10.1038/s41598-022-11417-z
https://hal.archives-ouvertes.fr/hal-03666597

Engineered neutral phosphorous dendrimers protect mouse cortical neurons and brain organoids from excitotoxic death
Posadas I., Romero-Castillo L., Ronca R.-A., Karpus A., Mignani S., Majoral J.-P., Muñoz-Fernández M., Ceña V.
International Journal of Molecular Sciences 2022, 23(8), 4391/1-16.
https://doi.org/10.3390/ijms23084391
https://hal.archives-ouvertes.fr/hal-03659072

Dendrimer nanoplatforms for veterinary medicine applications: A concise overview
Mignani S., Shi X., Rodrigues J., Tomás H., Majoral J.-P.
Drug Discovery Today 2022, 27(5), 1251-1260.
https://doi.org/10.1016/j.drudis.2022.01.001
https://hal.archives-ouvertes.fr/hal-03659120

Engineered phosphorus dendrimers as powerful non-viral nanoplatforms for gene delivery: A great hope for the future of cancer therapeutics
Mignani S., Shi X., Bryszewska M., Shcharbin D., Majoral J.-P.
Exploration of Targeted Anti-tumor Therapy 2022, 3(1), 50-61.
https://doi.org/10.37349/etat.2022.00071
https://hal.archives-ouvertes.fr/hal-03659099

Crown macromolecular derivatives: Stepwise design of new types of polyfunctionalized phosphorus dendrimers
Karpus A., Mignani S., Zablocka M., Majoral J.-P.
The Journal of Organic Chemistry 2022, 87(5), 3433-3441.
https://doi.org/10.1021/acs.joc.1c03009
https://hal.archives-ouvertes.fr/hal-03659036

PEG-cored phosphorus dendrimers: Synthesis and functionalization
Dib H., Rebière J., Rebout C., Alami O., El Kazzouli S., El Brahmi N., Laurent R., Delavaux-Nicot B., Caminade A.-M.
Results in Chemistry 2022, 4, 100304/1-10.
https://doi.org/10.1016/j.rechem.2022.100304
https://hal.archives-ouvertes.fr/hal-03578838

Amphiphilic triazine-phosphorus metallodendrons possessing anti-cancer stem cell activity
Apartsin E. K., Knauer N., Kahlert U. D., Caminade A.-M.
Pharmaceutics 2022, 14(2), 393/1-13.
https://doi.org/10.3390/pharmaceutics14020393
https://hal.archives-ouvertes.fr/hal-03660604

Dendriplex-impregnated hydrogels with programmed release rate
Apartsin E., Venyaminova A., Majoral J.-P., Caminade A.-M.
Frontiers in Chemistry 2022, 9, 780608/1-7.
https://doi.org/10.3389/fchem.2021.780608
https://hal.archives-ouvertes.fr/hal-03547654

2021

AB5 derivatives of cyclotriphosphazene
Caminade A.-M.
Encyclopedia Platform. MDPI: Bâle (Switzerland), 2021, Entry 12744.
https://encyclopedia.pub/entry/12744
https://hal.archives-ouvertes.fr/hal-03714118

AB5 derivatives of cyclotriphosphazene for the synthesis of dendrons and their applications
Zibarov A., Oukhrib A., Aujard Catot J., Turrin C.-O., Caminade A.-M.
Molecules 2021, 26(13), 4017/1-24.
https://doi.org/10.3390/molecules26134017
https://hal.archives-ouvertes.fr/hal-03378292

Fluctuations in AKT and PTEN activity are linked by the E3 ubiquitin ligase cCBL
Olazábal-Morán M., Sánchez-Ortega M., Martínez-Muñoz L., Hernández C., Rodríguez M. S., Mellado M., Carrera A. C.
Cells 2021, 10(11), 2803/1-21.
https://doi.org/10.3390/cells10112803
https://hal.archives-ouvertes.fr/hal-03728095

Impact of molecular rigidity on the gene delivery efficiency of core–shell tecto dendrimers
Wang D., Chen L., Gao Y., Song C., Ouyang Z., Li C., Mignani S., Majoral J.-P., Shi X., Shen M.
Journal of Materials Chemistry B 2021, 9(31), 6149-6154.
http://dx.doi.org/10.1039/D1TB01328A
https://hal.archives-ouvertes.fr/hal-03658965

Dendrimers functionalized with palladium complexes of N-, N,N-, and N,N,N-ligands
Vanbellingen Q., Servin P., Coinaud A., Mallet-Ladeira S., Laurent R., Caminade A.-M.
Molecules 2021, 26(8), 2333/1-19.
https://doi.org/10.3390/molecules26082333
https://hal.archives-ouvertes.fr/hal-03275902

Comparison of the effects of dendrimer, micelle and silver nanoparticles on phospholipase A2 structure
Terehova M., Dzmitruk V., Abashkin V., Kirakosyan G., Ghukasyan G., Bryszewska M., Pedziwiatr-Werbicka E., Ionov M., Gómez R., de la Mata F. J., Mignani S., Shi X., Majoral J.-P., Sukhodola A., Shcharbin D.
Journal of Biotechnology 2021, 331, 48-52.
https://doi.org/10.1016/j.jbiotec.2021.03.009
https://hal.archives-ouvertes.fr/hal-03245002

Blood compatibility of amphiphilic phosphorous dendrons—prospective drug nanocarriers
Suty S., Oravczova V., Garaiova Z., Subjakova V., Ionov M., Shcharbin D., Simonikova Z., Bartek P., Zvarik M., Shi X., Mignani S., Majoral J.-P., Bryszewska M., Hianik T., Waczulikova I.
Biomedicines 2021, 9(11), 1672/1-13.
https://doi.org/10.3390/biomedicines9111672
https://hal.archives-ouvertes.fr/hal-03658953

Facile synthesis of amphiphilic fluorescent phosphorus dendron-based micelles as antiproliferative agents: First investigations
Qiu J., Chen L., Zhan M., Laurent R., Bignon J., Mignani S., Shi X., Caminade A.-M., Majoral J.-P.
Bioconjugate Chemistry 2021, 32(2), 339-349.
https://doi.org/10.1021/acs.bioconjchem.0c00716
https://hal.archives-ouvertes.fr/hal-03148744

Phenyl-pyta-tricarbonylrhenium(i) complexes: combining a simplified structure and steric hindrance to modulate the photoluminescence properties
Poirot A., Vanucci-Bacqué C., Delavaux-Nicot B., Leygue N., Saffon-Merceron N., Alary F., Bedos-Belval F., Benoist E., Fery-Forgues S.
Dalton Transactions 2021, 50(39), 13686-13698.
http://dx.doi.org/10.1039/D1DT02161C
https://hal.archives-ouvertes.fr/hal-03358697

Dendrimeric HIV-peptide delivery nanosystem affects lipid membranes structure
Milowska K., Rodacka A., Melikishvili S., Buczkowski A., Pałecz B., Waczulikova I., Hianik T., Majoral J.-P., Ionov M., Bryszewska M.
Scientific Reports 2021, 11(1), 16810/1-12.
https://doi.org/10.1038/s41598-021-96194-x
https://hal.archives-ouvertes.fr/hal-03658931

Safe polycationic dendrimers as potent oral in vivo inhibitors of Mycobacterium tuberculosis: A new therapy to take down tuberculosis
Mignani S., Tripathi V. D., Soam D., Tripathi R. P., Das S., Singh S., Gandikota R., Laurent R., Karpus A., Caminade A.-M., Steinmetz A., Dasgupta A., Srivastava K. K., Majoral J.-P.
Biomacromolecules 2021, 22(6), 2659-2675.
https://doi.org/10.1021/acs.biomac.1c00355
https://hal.archives-ouvertes.fr/hal-03273968

Dendritic macromolecular architectures: Dendrimer-based polyion complex micelles
Mignani S., Shi X., Zablocka M., Majoral J.-P.
Biomacromolecules 2021, 22(2), 262-274.
https://doi.org/10.1021/acs.biomac.0c01645
https://hal.archives-ouvertes.fr/hal-03275792

Multivalent copper(II)-conjugated phosphorus dendrimers with noteworthy in vitro and in vivo antitumor activities: A concise overview
Mignani S., Shi X., Steinmetz A., Majoral J.-P.
Molecular Pharmaceutics 2021, 18(1), 65-73.
https://doi.org/10.1021/acs.molpharmaceut.0c00892
https://hal.archives-ouvertes.fr/hal-03275781

First-in-class and best-in-class dendrimer nanoplatforms from concept to clinic: Lessons learned moving forward
Mignani S., Shi X., Rodrigues J., Tomas H., Karpus A., Majoral J.-P.
European Journal of Medicinal Chemistry 2021, 219, 113456/1-14.
https://doi.org/10.1016/j.ejmech.2021.113456
https://hal.archives-ouvertes.fr/hal-03275575

Non-invasive intranasal administration route directly to the brain using dendrimer nanoplatforms: An opportunity to develop new CNS drugs
Mignani S., Shi X., Karpus A., Majoral J.-P.
European journal of medicinal chemistry 2021, 209, 112905/1-11.
https://doi.org/10.1016/j.ejmech.2020.112905
https://hal.archives-ouvertes.fr/hal-03203309

Functionalized dendrimer platforms as a new forefront arsenal targeting SARS-CoV-2: An opportunity
Mignani S., Shi X., Karpus A., Lentini G., Majoral J.-P.
Pharmaceutics 2021, 13(9), 1513/1-14.
https://doi.org/10.3390/pharmaceutics13091513
https://hal.archives-ouvertes.fr/hal-03657073

Clinical diagonal translation of nanoparticles: Case studies in dendrimer nanomedicine
Mignani S., Shi X., Guidolin K., Zheng G., Karpus A., Majoral J.-P.
Journal of Controlled Release 2021, 337, 356-370.
https://doi.org/10.1016/j.jconrel.2021.07.036
https://hal.archives-ouvertes.fr/hal-03657022

In vivo therapeutic applications of phosphorus dendrimers: state of the art
Mignani S., Shi X., Ceña V., Shcharbin D., Bryszewska M., Majoral J.-P.
Drug Discovery Today 2021, 26(3), 677-689.
https://doi.org/10.1016/j.drudis.2020.11.034
https://hal.archives-ouvertes.fr/hal-03274966

Engineered non-invasive functionalized dendrimer/dendron-entrapped/complexed gold nanoparticles as a novel class of theranostic (radio)pharmaceuticals in cancer therapy
Mignani S., Shi X., Ceña V., Rodrigues J., Tomas H., Majoral J.-P.
Journal of Controlled Release 2021, 332, 346-366.
https://doi.org/10.1016/j.jconrel.2021.03.003
https://hal.archives-ouvertes.fr/hal-03203301

First-in-class phosphorus dendritic framework, a wide surface functional group palette bringing noteworthy anti-cancer and anti-tuberculosis activities: what lessons to learn?
Mignani S., Bignon J., Shi X., Majoral J.-P.
Molecules 2021, 26(12), 3708/1-14.
https://doi.org/10.3390/molecules26123708
https://hal.archives-ouvertes.fr/hal-03656981

Hybrid phosphorus–viologen dendrimers as new soft nanoparticles: design and properties
Majoral J.-P., Zablocka M., Ciepluch K., Milowska K., Bryszewska M., Shcharbin D., Katir N., El Kadib A., Caminade A.-M., Mignani S.
Organic Chemistry Frontiers 2021, 8(16), 4607-4622.
http://dx.doi.org/10.1039/D1QO00511A
https://hal.archives-ouvertes.fr/hal-03275562

Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation
Lobato-Gil S., Heidelberger J. B., Maghames C., Bailly A., Brunello L., Rodriguez M. S., Beli P., Xirodimas D. P.
Cell Reports 2021, 34(3), 108635/1-15.
https://doi.org/10.1016/j.celrep.2020.108635
https://hal.archives-ouvertes.fr/hal-03176206

SALL1 modulates CBX4 stability, nuclear bodies, and regulation of target genes
Giordano I., Pirone L., Muratore V., Landaluze E., Pérez C., Lang V., Garde-Lapido E., Gonzalez-Lopez M., Barroso-Gomila O., Vertegaal A. C. O., Aransay A. M., Rodriguez J. A., Rodriguez M. S., Sutherland J. D., Barrio R.
Frontiers in Cell and Developmental Biology 2021, 9(2610), 715868/1-17.
https://doi.org/10.3389/fcell.2021.715868
https://hal.archives-ouvertes.fr/hal-03370040

SUMOylation modulates the stability and function of PI3K-p110β
El Motiam A., de la Cruz-Herrera C. F., Vidal S., Seoane R., Baz-Martínez M., Bouzaher Y. H., Lecona E., Esteban M., Rodríguez M. S., Vidal A., Collado M., Rivas C.
Cellular and molecular life sciences : CMLS 2021, 78, 4053-4065.
https://doi.org/10.1007/s00018-021-03826-6
https://hal.archives-ouvertes.fr/hal-03203257

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3-ITD-driven acute myeloid leukemia
Lopez-Reyes R. G., Quinet G., Gonzalez-Santamarta M., Larrue C., Sarry J.-E., Rodriguez M. S.
FEBS Open Bio 2021, 11(1), 48-60.
https://doi.org/10.1002/2211-5463.12950
https://hal.archives-ouvertes.fr/hal-03007137

The usefulness of trivalent phosphorus for the synthesis of dendrimers
Caminade A.-M., Moineau-Chane Ching K. I., Delavaux-Nicot B.
Molecules 2021, 26(2), 269/1-30.
https://doi.org/10.3390/molecules26020269
https://hal.archives-ouvertes.fr/hal-03131217

Dendritic metal complexes for bioimaging. Recent advances
Caminade A.-M., Hameau A., Turrin C.-O., Laurent R., Majoral J.-P.
Coordination Chemistry Reviews 2021, 430, 213739/1-27.
https://doi.org/10.1016/j.ccr.2020.213739
https://hal.archives-ouvertes.fr/hal-03131731

Mechanical modulation of the solid-state luminescence of tricarbonyl rhenium(I) complexes through the interplay between two triplet excited states
Calupitan J. P., Poirot A., Wang J., Delavaux-Nicot B., Wolff M., Jaworska M., Métivier R., Benoist E., Allain C., Fery-Forgues S.
Chemistry – A European Journal 2021, 27(12), 4191-4196.
https://doi.org/10.1002/chem.202005245
https://hal.archives-ouvertes.fr/hal-03130077

Electron transfer inside a decaferrocenylated rotaxane analyzed by fast scan cyclic voltammetry and impedance spectroscopy
Boitel-Aullen G., Fillaud L., Huet F., Nierengarten I., Delavaux-Nicot B., Nierengarten J.-.F, Maisonhaute E.
ChemElectroChem 2021, 8(18), 3506-3511.
https://doi.org/10.1002/celc.202100738
https://hal.archives-ouvertes.fr/hal-03292071

Supramolecular self-associations of amphiphilic dendrons and their properties
Apartsin E., Caminade A.-M.
Chemistry – A European Journal 2021, 27(72), 17976-17998.
https://doi.org/10.1002/chem.202102589
https://hal.archives-ouvertes.fr/hal-03547718

Copper complexes of phosphorus dendrimers and their properties
Alami O., Laurent R., Majoral J.-P., El Brahmi N., El Kazzouli S., Caminade A.-M.
Inorganica Chimica Acta 2021, 517, 120212/1-8.
https://doi.org/10.1016/j.ica.2020.120212
https://hal.archives-ouvertes.fr/hal-03131594

Partnerships

Click here to consult the partners
  • Technopolym 

The team is a partner of Technopolym, scientific service of the “Institut de Chimie deToulouse”, specialized in the characterization of polymers and polymer materials: chromatographic studies, characterization of thermal behaviour, physicochemical characterizations, physical and mechanical properties.
Technopolym is by nature open to everyone, academic laboratories or industries.
To contact Technopolym:  ict.technopolym@univ-tlse3.fr
Platform manager : Pascale LABORIE (IGE UPS) (pascale.laborie(at)univ-tlse3.fr)
Scientific referent: Régis LAURENT (regis.laurent(at)lcc-toulouse.fr)
Download Technopolym flyer (.pdf file)

 

  • International Collaborations
    • Germany
      Dietmar Appelhans (Dresden)
      Evamarie Hey-Hawkins (Leipzig)
      Oliver Reiser (Regensburg)
    • Austria
      Wolfgang Knoll (Vienna)
    • Belarus
      Dimitri Shcharbin (Minsk)
    • Canada
      Anton Shakhbazau (Calgary)
    • China
      Xiangyang Shi (Shanghai)
    • South Korea
      Dong Ha Kim (Seoul)
    • Spain
      Rosa Barrio (Bilbao)
      Victorio Cadierno (Oviedo)
      Valentin Cena (Albacete)
      Agusti Lledos (Barcelona)
      Nazario Martin (Madrid)
      Francisco J. de la Mata de la Mata (Alcala de Henares)
      Maria Angeles Munoz-Fernandez (Madrid)
      Enrique Orti (Valencia)
      Anna Pla-Quintana (Girona)
      Niels Reichardt (San Sebastian)
      Carmen Rivas (Santiago de Compostela)
      Antonio Romerosa (Almeria)
      Gaël Roué (Barcelona)
      Rosa Maria Sebastian (Barcelona)
      José Vidal-Gancedo (Barcelona)
    • Italy
      Nicola Armaroli (Bologna)
      Germana Meroni (Trieste)
      Francesca Ottaviani (Urbino)
      Anna Painelli (Parma)
      Maurizio Peruzzini (Firenze)
    • Morocco
      Mosto M. Bousmina (Fes)
      Nabil El Brahmi (Fes)
      Said El Kazzouli (Fes)
      Abdelkrim El Khadid (Fes)
      Mohamed Hajjaji (Marrakech)
    • Mexico
      Ernesto Rivera (Mexico City)
    • Poland
      Maria Bryszewska (Lodz)
      Barbara Klajnert (Lodz)
      Maria Zablocka (Lodz)
    • Portugal
      Rune Matthiesen (Lisbon)
      Joao Rodrigues (Madeira)
    • United Kingdom
      Ronald T. Hay (Dundee)
    • Russia
      Evgeny Apartsin (Novosibirsk)
      Victor Furer (Kazan)
      Valeri Kovalenko (Kazan)
      Daria Novoprashina (Novosibirsk)
  • National collaborations
    Jérôme Bignon (Gif sur Yvette)
    Mireille Blanchard-Desce (Bordeaux)
    Laurence Charles (Marseille)
    Bertrand Donnio (Strasbourg)
    Elias Fattal (Chatenay Malabry)
    Emmanuel Maisonhaute (Paris)
    Oleg Melnyck (Lille)
    Serge Mignani (Paris)
    Jean-François Nierengarten (Strasbourg)
    Armelle Ouali (Montpellier)
    Jean-Christophe Rain (Paris)
    Jean-Pierre Sauvage (Strasbourg)
    Marc Taillefer (Montpellier)
    Jean-Baptiste Verlhac (Bordeaux)
    Dimitris Xirodimas (Montpellier)

 

  • Toulouse collaborations
    Fabienne Alary
    Muriel Blanzat
    Georges Czaplicki
    Suzanne Fery-Forgues
    Jean-Marie François
    Yves Génisson
    Muriel Golzio
    Jérôme Nigou
    François Malecaze
    Eric Manoury (LCC)
    Rémy Poupot
    Karine Reybier-Vuattoux
    Emmanuelle Trévisiol

Funding

Click here to consult the funders
  • H2020-MSCA-ITN-2019 EJD 860322 CCIMC: Coordination Chemistry Inspires Molecular Catalysis
    Deputy Coordinator : Anne-Marie Caminade 2020-2024.
  • ARC Foundation for Cancer Research
    PhD Supervisor: Manuel S. Rodriguez
    Beneficiary : Maria Gonzalez Santamarta (2021-2022)
  • Marie Slodowska Curie Actions UbiCODE: European training network to decipher the Ubiquitin Code (GA 765445)
    Coordinators: Manuel S. Rodriguez, Rosa Barrio (Spain) (2018-2022)
  • Occitanie Region:
    Support to laboratory innovation efforts – UbiPièges
    Coordinator: Manuel S. Rodriguez (2019-2022)
  • Occitanie Region: Reinforcement of European Research projects in collaboration with companies
    Coordinator: Manuel S. Rodriguez (2019-2021)
  • Creation of the China France Joint laboratory for healthcare theranostics (LCC, Donghua University, Shanghai).
    French Coordinators Jean-Pierre Majoral and Serge Mignani
    Chinese Coordinator Prof X. Shi.
  • Euronanomed III project: Nanomedicine for glioblastoma therapy / acronyme NANOGLIO.
    French Coordinator: Jean Pierre Majoral
    Scientific Partner: Anne-Marie Caminade 2019-2022.
  • MSCA IF EUREKA (Marie Slodowska-Curie Action) : Multifunctional dendrimers as vectors of therapeutic siRNA.
    French coordinator: Anne-Marie Caminade 2020-2022.
  • Programme PRC 2019 CNRS-NSCF (France-China): Dendrimers against triple negative breast cancer.
    French coordinator: Anne-Marie Caminade, co-coordinators: Serge Mignani, Jean Pierre Majoral 2019-2021.
  • Programme TOUBKAL (Franco-Marocain) : L’oxyde de graphène et les nanotubes de carbone fonctionnalisés par des dendrons et dendrimères phosphorés pour des applications en oncologie.
    French coordinator: Anne-Marie Caminade 2019-2022.
    Moroccan coordinator: Nabil El Brahmi
  • Contrat Agro Innovation International ENCAPS: Encapsulation and release of active substances by dendrimers.
    Anne-Marie Caminade 2019.
  • Programme de soutien à la recherche SIIRI (Québec, France, Espagne) : Nanomatériaux dendritiques comme vecteurs non-viraux pour la livraison de médicaments et de gènes contre le cancer du sein.
    French partners: Anne-Marie Caminade and Jean-Pierre Majoral 2018-2020.
  • ANR 2017 PRC CE9 SLOW2 : Stereo Laser Writing On Water
    Coordinator: Anne-Marie Caminade 2017-2022.
  • GDR CNRS : Phosphore
    WP3 leader « Molécules bioactives et applications » : Anne-Marie Caminade 2017-2021.
  • China Scholarship Council project: Design and properties of biocompatible phosphorus dendrimers to tackle cancers.
    French coordinator: Jean Pierre Majoral 2016-2019
  • Programme COFECUB CAPES (franco-brésilien) : Développement de nanovecteurs pour le traitement de pathologies du système nerveux central.
    French coordinator: Muriel Blanzat (Toulouse)
    Partner: Cédric-Olivier Turrin 2016-2018.
  • Projet VML : Nouveaux dendrimères polypharmacophoriques pour une stratégie thérapeutique duale innovante contre la maladie de Gaucher.
    Coordinator: Yves Génisson (Toulouse)
    Partner: Cédric-Olivier Turrin 2016-2018.
  • CEFIPRA (France-India) : Préparation de dendrimères phosphorés originaux pour lutter contre la tuberculose pulmonaire.
    French coordinator: Anne-Marie Caminade, co-coordinators: Serge Mignani, Jean Pierre Majoral 2015-2019.
  • Réseau GDRI HC3A : Hetero-elements and Coordination Chemistry: from the Concept to Applications.
    Coordinator: Montserat Gomez (Toulouse).
    Team leader: Anne-Marie Caminade 2015-2022.
  • ANR PRTS TREE-DRUG: Development of a drug-candidate: a phosphorus-based dendrimer with anti-inflammatory and immuno-modulatory properties.
    Coordinator: Rémy Poupot (Toulouse)
    Partner: Cédric-Olivier Turrin 2014-2017.
  • Réseau Marie Curie Actions People International Research Staff Exchange Scheme (PIRSES): NANOGEN EU –Belarus-Russia Network in Nanomaterials-Driven Anti-Cancer gene therapy.
    French coordinator : Jean Pierre Majoral 2014-2016
  • Réseau COST CM1302 SIPs: Smart Inorganic Polymers.
    Coordinator: Evamarie Hey-Hawkins (Germany)
    Leader Working group 2: Anne-Marie Caminade 2013-2017
  • China Schorlarship Council project: Design, synthesis and characterization of new organic semi-conductors for photovoltaics.
    Thesis supervisor : Kathleen Moineau-Chane Ching 2013-2016
  • IDEX Université de Toulouse Programme « Nouveaux Entrants » Aurélien Hameau 2013
  • FRM Chimie pour la Médecine : Recherche du/des récepteur(s) spécifique(s) d’un dendrimère phosphoré, candidat-médicament immuno-modulateur.
    Coordinator: Anne-Marie Caminade 2011-2015
  • ANR Blanc COPPERTREE : Traitement antibiofilm de surface par dépôt multicouches de dendrimères et de nanoparticules de cuivre.
    Coordinator: Cédric-Olivier Turrin 2011-2015.
  • CONACyT Scholarship : Photovoltaïque organique : étude de la morphologie de films minces ; conception, synthèse et étude de petites molécules organiques.
    Thesis supervisor: Kathleen Moineau-Chane Ching 2011-2015
  • Contrat COMUE-Région : Photovoltaique Organique : étude des intéractions electroniques aux interfaces des hétérojonctions organiques.
    Thesis supervisor: Kathleen Moineau-Chane Ching 2011-2015
  • ANR Blanc Click-unclick : Assemblage/désassemblage de systèmes prodrogue innovants grâce à une stratégie de chimie Click-Unclick.
    Coordinator: Oleg Melnyk (Lille)
    Partner: Anne-Marie Caminade 2011-2014
  • ANR RPIB 2011 DENDRI’MS : Traitement de la Sclérose en Plaques par un dendrimère phosphoré immuno-modulateur.
    Coordinator: Rémy Poupot (Toulouse)
    Partner: Anne-Marie Caminade 2011-2014
  • CE FP7 SUDOE Interreg IVB, SOE2/P1/E341 CliNK : Nouveaux protocoles de l’immunothérapie : Production de cellules NK activées pour une utilisation clinique.
    Coordinator: Alberto Anel (Espagne)
    Team leader: Anne-Marie Caminade 2011-2013
  • GDR Electronique Organique N° 3368.
    Coordinator: Lionel Hirsch (Bordeaux)
    Steering committee member: Kathleen Moineau-Chane Ching 2010-2018
  • ANR Blanche Internationale Franco-Allemande DENDSWITCH : Dendrimères modifiables par stimulation. Vers des catalyseurs adaptables.
    French coordinator: Anne-Marie Caminade (Evamarie Hey-Hawkins côté Allemand) 2010-2013
  • ANR Emergence INNO-THER-RA : Les dendrimères phosphorés : Molécules innovantes pour le traitement de la Polyarthrite Rhumatoïde.
    Coordinator: Rémy Poupot (Toulouse)
    Partner: Anne-Marie Caminade 2010-2013
  • EuroNanomed European Innovative RTD project proposals in Nanomedicine DENPEPT HIV: Peptide-associated dendrimers in dendritic cells for the development of new nano-HIV vaccines.
    Coordinator: Maria Angeles Munoz Fernandez (Espagne)
    French coordinator: Jean Pierre Majoral 2010-2012
  • Accord Institut Inanotech (Rabat Morocco) – LCC.
    Coordinator: Jean Pierre Majoral 2009-2014
  • Réseau COST TD0802 Biodendrimers: Biomedical applications of dendrimers.
    Coordinator: Barbara Klajnert (Pologne)
    Jean-Pierre Majoral (MC) Anne-Marie Caminade (MC Substitute) 2009-2013
  • ANR Blanche Internationale Franco-Allemande GLOBUCAT : Environmental friendly homogeneous and heterogeneous catalysis.
    French coordinator: Jean Pierre Majoral (Oliver Reiser Germany) 2009-2012
  • Réseau COST CM0802 PhoSciNet: Phosphorus Science Network.
    Coordinator: Evamarie Hey-Hawkins (Germany)
    Vice-leader Working Group 4: Anne-Marie Caminade 2008-2012.
  • Réseau LIA LCMMF : Laboratoire de Chimie Moléculaire Marocco-Français.
    Coordinator: Jean-Jacques Bonnet (Toulouse)
    Team leader: Anne-Marie Caminade 2008-20155
  • ANR Physique et Chimie du Vivant PCV BIODENDRIDOT : Fluorophores dendritiques à 2 photons pour l’imagerie moléculaire, sub-cellulaire et cellulaire et chez l’animal vivant.
    Coordinator: Anne-Marie Caminade 2007-2010
  • Commission EuropéenneCNRS : Projet OLLA (Organic LED’s for lighting and ICT applications).
    Coordinator: Philips Electronics
    De la préparation de complexes du Cu(I) luminescents à l’auto assemblage de systèmes supramoléculaires complexes.
    Thesis supervisor: Béatrice Delavaux-Nicot 2005-2008.
  • Réseau LEA LTPMM : Laboratoire Trans-Pyrénéen : de la Molécule aux Matériaux.
    Coordinator: Antoine Baceiredo (Toulouse)
    Team leader: Anne-Marie Caminade 2006-2013
  • Contrat IFP (Institut Français du Pétrole)
    Anne-Marie Caminade 2005-2008

Address

Laboratoire de chimie de coordination du CNRS

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