Metallomimetic C–F Activation Catalysis by Simple Phosphines


Study published in the Journal of the American Chemical Society.

In order to develop new fluorinated molecules with applications in healthcare, agriculture or even for batteries, it is necessary to split the strong carbon-fluorine bond. This is achieved by using electron-rich metallic species that are difficult to manipulate and are based on scarce and sometimes toxic chemical elements. Scientists have shown that simple phosphorus-based agents are capable of breaking down these carbon-fluorine bonds in a similar way to metals. This work opens the way to more sustainable synthesis of organofluorinated compounds.


 © Antoine Simonneau


Sara Bonfante, Christian Lorber, Jason M. Lynam, Antoine Simonneau, John M. Slattery
Metallomimetic C-F activation catalysis by simple phosphines

Journal of the American Chemical Society 2023


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