Laboratoire COBRA, CNRS, INSA Rouen et Université de Rouen
Bât IRCOF, 1 rue Lucien Tesnière, 76821 Mont-Saint-Aignan
julien.legros@univ-rouen.fr | www.lab-cobra.fr | https://gdrsynth-flux.cnrs.fr/
(1) Monbaliu, J.-C. M.; Legros, J. Will the next Generation of Chemical Plants Be in Miniaturized Flow Reactors? Lab Chip 2023, 23 (5), 1349–1357. https://doi.org/10.1039/D2LC00796G.
(2) Descroix, S.; Legros, J.; Salmon, J.-B. Faire Mieux Avec Moins : La Microfluidique ! In Etonnante Chimie; Pradier, C.-M., Series Ed.; CNRS Editions: Paris, 2021.
(3) Desrues, T.; Legros, J.; Jubault, P.; Poisson, T. Flow Synthesis of an α-Amino Boronic Ester as a Key Precursor of Bortezomib Drug. React. Chem. Eng. 2022, 7 (6), 1285–1288. https://doi.org/10.1039/D2RE00099G.
(4) Brégent, T.; Ivanova, M. V.; Poisson, T.; Jubault, P.; Legros, J. Continuous-Flow Divergent Lithiation of 2,3-Dihalopyridines: Deprotolithiation versus Halogen Dance. Chem. Eur. J. 2022, 28 (71), e202202286. https://doi.org/10.1002/chem.202202286.
(5) Silva, V. B.; Mansour, S.; Delaune, A.; Felpin, F.-X.; Legros, J. Flow Detoxification of a Sulfur Mustard Simulant with Organometallic Compounds Enabled by an Optimization Algorithm. Soumis.
(6) Picard, B.; Gouilleux, B.; Lebleu, T.; Maddaluno, J.; Chataigner, I.; Penhoat, M.; Felpin, F.-X.; Giraudeau, P.; Legros, J. Oxidative Neutralization of Mustard-Gas Simulants in an On-Board Flow Device with In-Line NMR Monitoring. Angew. Chem. Int. Ed. 2017, 56 (26), 7568–7572. https://doi.org/10.1002/anie.201702744.
(7) Delaune, A.; Mansour, S.; Picard, B.; Carrasqueira, P.; Chataigner, I.; Jean, L.; Renard, P.-Y.; Monbaliu, J.-C. M.; Legros, J. Flow Neutralisation of Sulfur-Containing Chemical Warfare Agents with Oxone: Packed Bed vs. Aqueous Solution. Green Chem. 2021, 23 (8), 2925–2930. https://doi.org/10.1039/D1GC00449B.
